陳垣崇 博士Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis.
Nature Medicine., Nov 23, 2008
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening adverse drug reactions characterized by massive ......
陳垣崇 博士Mutations in the SLC2A10 gene cause arterial abnormalities in mice
Cardiovascular Research., Nov 21, 2008
Aims: Glucose transporter 10 (GLUT10), encoded by the SLC2A10 gene, is a member of the class III facilitative glucose transporter family. ......
潘文涵 博士Is Ischemic Stroke Risk Related to Folate Status or Other Nutrients Correlated With Folate Intake?
American Stroke Association, Nov 06, 2008
Folate status was inversely associated with plasma homocysteine concentration, a potential risk factor of cardiovascular disease. However ......
林小喬 博士Common physical basis of macromolecule-binding sites in proteins.
Nucleic Acids Research, Nov 06, 2008
Protein–DNA/RNA/protein interactions play critical roles in many biological functions. Previous studies have focused on the differe ......
沈志陽 博士Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair.
The EMBO Journal, Oct 30, 2008
The DNA damage response (DDR) has an essential function in maintaining genomic stability. Ataxia telangiectasia-mutated (ATM)-checkpoint ......
譚婉玉 博士The RNA binding protein hnRNP Q modulates the utilization of exon 7 in the survival motor neuron 2 (SMN2) gene.
MCB., Sep 15, 2008
Spinal muscular atrophy (SMA) is a recessive neuromuscular disorder caused by the homozygous loss of the SMN1 gene. The human SMN2 gene h ......
楊泮池 博士Claudin-1 is a Metastasis Suppressor and Correlates with Clinical Outcome in Lung Adenocarcinoma.
Am. J. Respir. Crit. Care Med., Sep 11, 2008
Rationale: Claudin-1(CLDN1), a key component of tight junction complexes, was down-regulated in human lung adenocarcinomas. Objectives: T ......
潘文涵 博士Lipoprotein lipase variants associated with an endophenotype of hypertension: hypertension combined with elevated triglycerides.
Hum Mutat., Jul 22, 2008
Previously, we observed that young-onset hypertension was independently associated with elevated plasma triglyceride(s) (TG) levels to a ......
張久瑗 博士CD44 Engagement Promotes Matrix-derived Survival through CD44-SRC-integrin Axis in Lipid Rafts.
Mol. Cell. Biol., Jul 21, 2008
CD44 is present in detergent-resistant cholesterol-rich microdomains, called lipid rafts, in many types of cells. However, the functional ......
譚婉玉 博士The DEAD-box RNA Helicase DDX3 Associates with Export mRNPs as well as TAP and Participates in Translational Control.
Mol Biol Cell., Jul 02, 2008
Monitoring Editor: Peter Walter Nuclear export of mRNA is tightly linked to transcription, nuclear mRNA processing, and subsequent matura ......
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