Dr. Cheng, Andrew Tai Ann Variant GADL1 and Response to Lithium Therapy in Bipolar I Disorder.
N Engl J Med., Dec 25, 2013Background Lithium has been a first-line choice for maintenance treatment of bipolar disorders to prevent relapse of mania and depression, b ......
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Dr. Chen, Chinpan Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae.
Nucl. Acids Res., Dec 25, 2013Klebsiella pneumoniae PmrA is a polymyxin-resistance-associated response regulator. The C-terminal effector/DNA-binding domain of PmrA (PmrA ......
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Dr. Chang, Chen Negative cerebral blood volume fMRI response coupled with Ca2+-dependent brain activity in a dopaminergic road map of nociception.
Neuroimage, Dec 22, 2013Decreased cerebral blood volume/flow (CBV/CBF) contributes to negative blood-oxygen-level-dependent (BOLD) functional MRI (fMRI) signals. Bu ......
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Dr. Lin, Teng-Nan 15-Deoxy-∆12,14-PGJ 2, by Activating Peroxisome Proliferator-Activated Receptor-Gamma, Suppresses p22phox Transcription to Protect Brain Endothelial Cells Against Hypoxia-Induced Apoptosis.
Mol Neurobiol., Dec 19, 201315-Deoxy-∆12,14-PGJ2 (15d-PGJ2) and thiazolidinedione attenuate reactive oxygen species (ROS) production via a peroxisome proliferator-activ ......
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Dr. Shih, Chiaho Nucleic Acid Chaperone Activity Associated with the ARD Domain of Human Hepatitis B Virus Core Protein.
J Virol., Dec 18, 2013Hepatitis B virus (HBV) DNA replication occurs within the HBV icosahedral core particles. HBV core protein (HBc) contains an arginine-rich d ......
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Dr. Lim, Carmay Identifying RNA-binding residues based on evolutionary conserved structural and energetic features.
Nucl. Acids Res., Dec 16, 2013Increasing numbers of protein structures are solved each year, but many of these structures belong to proteins whose sequences are homologou ......
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Dr. Tang, Tang K. (invited News and Views article) Centriole biogenesis in multiciliated cells.
Nat Cell Biol., Dec 02, 2013Centrioles duplicate only once per cell cycle in proliferating cells, whereas in multiciliated cells, hundreds of centrioles form almost sim ......
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Dr. Chern, Yijuang The A2A adenosine receptor is a dual-coding gene: a novel mechanism of gene usage and signal transduction.
JBC, Nov 29, 2013The A2A adenosine receptor (A2AR) is a G protein-coupled receptor and a major target of caffeine. The A2AR gene encodes alternative transcri ......
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Dr. Yang, Ruey-Bing (Ray)Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition
J Cell Sci., Nov 08, 2013SCUBE2 (signal peptide-CUB-EGF domain-containing protein 2) belongs to a secreted and membrane-associated multi-domain SCUBE protein family. ......
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Dr. Huang, Yi-Shuian Deletion of CPEB3 Enhances Hippocampus-Dependent Memory via Increasing Expressions of PSD95 and NMDA Receptors.
J Neurosci., Oct 23, 2013Long-term memory requires activity-dependent synthesis of plasticity-related proteins (PRPs) to strengthen synaptic efficacy and consequentl ......
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