Dr. Chen, Chinpan 's publons link picture

Dr. Chen, Chinpan

Emeritus Research Fellow
  • 02-26523035 (Lab) (Room No: N133)
  • 02-27887641 (Fax)

  • Structural Biology
  • NMR

Education and Positions:
  • Ph.D. University of Washington

Highlight Detail

Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae.

Dr. Chen, Chinpan
Nucl. Acids Res., Dec 25, 2013

Klebsiella pneumoniae PmrA is a polymyxin-resistance-associated response regulator. The C-terminal effector/DNA-binding domain of PmrA (PmrAC) recognizes tandem imperfect repeat sequences on the promoters of genes to induce antimicrobial peptide resistance after phosphorylation and dimerization of its N-terminal receiver domain (PmrAN).