CBAP interacts with the un-liganded common b-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction.
Dr. Yen, Jeffrey J.Y.
Oncogene., Sep 10, 2007
The cytoplasmic domain of the common -chain (c) of the granulocyte–macrophage-colony-stimulating factor (GM-CSF)/interleukin-3 (IL-3)/IL-5 receptor contains a membrane proximal region that is sufficient to