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Dr. Lin, Yi-Ling

Distinguished Research Fellow
Division Chief
  • 02-2789-9013 (Lab) (Room No: 443)
  • 02-2652-3902
  • 02-2785-8847 (Fax)

  • Molecular Virology
  • Viral Pathogenesis
  • Viral Immunology

Education and Positions:
  • 1992, PhD, University of California, Los Angeles (UCLA), USA

    2020 ~ date, CEO, Emerging Infectious Disease Division (EIDD), Biomedical Translation Research Center (BioTReC), Academia Sinica


    Contact Information:

Highlight Detail

Japanese Encephalitis Virus Nonstructural Protein NS5 Interacts with Mitochondrial Trifunctional Protein and Impairs Fatty Acid β-Oxidation.

Dr. Lin, Yi-Ling
PLoS Pathog., May 27, 2015

Infection with Japanese encephalitis virus (JEV) can induce the expression of pro-inflammatory cytokines and cause acute encephalitis in humans. ?-oxidation breaks down fatty acids for ATP production in mitochondria, and impaired ?-oxidation can induce pro-inflammatory cytokine expression. To address the role of fatty-acid ?-oxidation in JEV infection, we measured the oxygen consumption rate of mock- and JEV-infected cells cultured with or without