Dr. Chern, Yijuang 's publons link picture

Dr. Chern, Yijuang

Distinguished Research Fellow
  • +886227899028 (Lab) (Room No: N333)
  • +886226523913 (Office)
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  • Signal Transduction
  • Gene Regulation
  • Neurodegeneration Disease

Education and Positions:
  • Ph.D. Univ. of Massachusetts

Highlight Detail

Aberrant astrocytes impair vascular reactivity in huntington's disease.

Dr. Chern, Yijuang
Ann Neurol., Apr 25, 2015

Objective Huntington's disease (HD) is an inherited neurodegenerative disease caused by the mutant Huntingtin gene (mHTT), which harbors expanded CAG repeats. We previously reported that the brain vessel density is higher in mice and patients with HD than in controls. The present study determines whether the vascular function is altered in HD and characterizes the underlying mechanism.