Dr. Shieh, Sheau-Yann 's publons link picture

Dr. Shieh, Sheau-Yann

Research Fellow
  • 02-26523916 (Lab) (Room No: N347)
  • 02-27829143 (Fax)

  • Cancer Cell Biology
  • Cell Cycle Signaling

Education and Positions:
  • Ph.D. Baylor College of Medicine Post-doc:Columbia University

Highlight Detail

The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1.

Dr. Shieh, Sheau-Yann
Oncogene, Jan 19, 2009

Cell cycle progression is monitored constantly to ensure faithful passage of genetic codes and genome stability. We have demonstrated previously that, upon DNA damage, TTK/hMps1 activates the checkpoint kinase CHK2 by phosphorylating CHK2 at Thr68.