Dr. Shieh, Sheau-Yann 's publons link picture

Dr. Shieh, Sheau-Yann

Research Fellow
  • 02-26523916 (Lab) (Room No: N347)
  • 02-27829143 (Fax)

  • Cancer Cell Biology
  • Cell Cycle Signaling

Education and Positions:
  • Ph.D. Baylor College of Medicine Post-doc:Columbia University

Highlight Detail

Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress.

Dr. Shieh, Sheau-Yann
Oncogene, Mar 30, 2009

Human checkpoint kinase 1 (CHK1) is an essential kinase required to preserve genome stability, and is activated by DNA replication blockage through the ataxia-telangiectasia-mutated-and-Rad3-related (ATR)/ATRIP-signaling pathway.