Dr. Shieh, Ru-Chi

Research Fellow
Specialty:
  • Biophysics/Electrophysics
  • Fluorescence/Ion Chennel
  • Thermodynamics
Education and Positions:

  • Ph.D. University of Rochester

Dr. Shieh, Ru-Chi 's
Publications

Journal 23 Book 0

  1. Sigg DM, Chang HK, Shieh RC Linkage analysis reveals allosteric coupling in Kir2.1 channels. The Journal of general physiology 150(11), 1541-1553 (2018) [JCR] [WOS]
  2. Liu CH, Chang HK, Lee SP, Shieh RC Activation of the Ca2+-sensing receptors increases currents through inward rectifier K+ channels via activation of phosphatidylinositol 4-kinase. Pflugers Archiv : European journal of physiology 468(11-12), 1931-1943 (2016) [JCR] [WOS]
  3. Chang HK, Iwamoto M, Oiki S, Shieh RC Mechanism for attenuated outward conductance induced by mutations in the cytoplasmic pore of Kir2.1 channels. Scientific reports 5, 18404 (2015) [JCR] [WOS]
  4. Hsueh-Kai Chang and Ru-Chi Shieh Voltage-dependent inhibition of Kir2.1 outward currents by extracellular spermine BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1828, 765-775 (2013-02) [JCR] [WOS]
  5. T-A Liu; H-K Chang; (R-C Shieh*) . Revisiting Inward Rectification: K Ions Permeate through Kir2.1 Channels during High-Affinity Block by Spermidine. JOURNAL OF GENERAL PHYSIOLOGY 139, 245-259 (2012-02) [JCR] [WOS]
  6. T-A Liu; H-K Chang; (R-C Shieh*) Extracellular K+ elevates outward currents through Kir2.1 channels by increasing single-channel conductance. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1808(6), 1772-1778 (2011-06) [JCR] [WOS]
  7. Hsueh-Kai Chang, Jay-Ron Lee, Tai-An Liu, Ching-Shu Suen, Jorge Arreola, and Ru-Chi Shieh* The extracellular K+ concentration-dependence of outward currents through Kir2.1 channels is regulated by extracellular Na+ and Ca2+. JOURNAL OF BIOLOGICAL CHEMISTRY 285(30), 23115-23125 (2010) [JCR] [WOS]
  8. Kun-Chi Chiang, Ling-Ping Lai, and *Ru-Chi Shieh** Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome. JOURNAL OF BIOMEDICAL SCIENCE 16, 76 (2009) [JCR] [WOS]
  9. Hsueh-Kai Chang, Laurence J. Marton, Kuo Kan Liang, and *Ru-Chi Shieh K^+ binding in the G-loop and water cavity facilitates Ba^2+ movement in the Kir2.1 channel. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1788, 500-506 (2009) [JCR] [WOS]
  10. Hsuan-Wen Hwang, Jay-Ron Lee, Kuan-Yu Chou, Ching-Shu Suen, Ming-Jing Hwang, Chinpan Chen, *Ru-Chi Shieh*, Lee-Young Chau** Oligomerization is crucial for the stability and function of heme oxygenase-1 in the endoplasmic reticulum. JOURNAL OF BIOLOGICAL CHEMISTRY 284(34), 22672-22679 (2009) [JCR] [WOS]
Dr. Chern, Yijuang's Lab