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中文
Dr. Lee, Eminy H.Y.
Distinguished Research Fellow
02-27899125 (Lab) (Room No: 308)
02-27829224 (Fax)
Specialty:
Pathogenesis of and Neuroprotection against Alzheimer's Disease
Molecular Mechanism of Mammalian Long-Term Memory Formation
Education and Positions:
Ph.D. Univ. of California, San Diego
Dr. Lee, Eminy H.Y. 's
Publications
Dr. Lee, Eminy H.Y. 's Lab
Dr. Lee, Eminy H.Y. 's Publications
Journal
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Chiou H.Y., Liu S.Y., Lin C.H. and Lee E.H.Y.*
Hes-1 SUMOylation by PIAS1 enhances the suppressing effect of Hes-1 on GADD45 alpha expression to increase cell survival
J. Biomed. Sci. 21, 53-75 (2014-07)
[JCR]
[WOS]
Hsu W.L., Ma Y.L., Hsieh D.Y., Liu Y.C. and Lee E.H.Y.*
STAT1 negatively regulates spatial memory formation and mediates the memory-impairing effect of amyloid-beta
Neuropsychopharmacology 39, 746-758 (2014-03)
[JCR]
[WOS]
Liu S.Y., Ma Y.L. and Lee E.H.Y.*
NMDA receptor signaling mediates the expression of protein inhibitor of activated STAT1 (PIAS1) in rat hippocampus
Neuropharmacology 65, 101-113 (2013-05)
[JCR]
[WOS]
Lin C.H. and Lee E.H.Y.*
JNK1 inhibits GluR1 expression and GluR1-mediated calcium influx through phosphorylation and stabilization of Hes-1.
J. Neurosci. 32(5), 1826-1846 (2012)
[JCR]
[WOS]
Chao C.C., Ma Y.L. and Lee E.H.Y.*
BDNF enhances Bcl-xL expression through protein kinase CK2-activated and NF-kB-mediated pathway in rat hippocampus.
Brain Pathology 21, 150-162 (2011)
[JCR]
[WOS]
Yang Y.C., Ma Y.L., Liu W.T. and Lee E.H.Y.*
Laminin beta1 impairs spatial learning through inhibition of ERK and SGK1 signaling.
Neuropsychopharmacology 36, 2571-2586 (2011)
[JCR]
[WOS]
Tai J.C., Hsu W.L., Liu Y.C., Ma Y.L. and Lee E.H.Y.*
Novel role and mechanism of protein inhibitor of activated STAT1 in spatial learning. (This paper is selected for highlighting by the International Molecular Biology Network and the Nature Publishing Group).
EMBO J. 30, 205-220 (2011)
[JCR]
[WOS]
Hsu W.L., Chiu T.H., Tai J.C., Ma Y.L. and Lee E.H.Y.*
A novel defense mechanism that is activated on amyloid-beta insult to mediate cell survival: role of SGK1-STAT1/STAT2 signaling.
Cell Death and Differentiation 16, 1515-1529 (2009-11)
[JCR]
[WOS]
Tai J.C., Su C.C., Ma Y.L. and Lee E.H.Y.*
SGK1 phosphorylation of I{kappa}B kinase {alpha} and p300 up-regulates NF-{kappa}B activity and increases N-methyl-D-aspartate receptor NR2A and NR2B expression.
J. Biol. Chem. 284(7), 4073-4089 (2009-02)
[JCR]
[WOS]
Tyan S.W., Tsai M.C., Lin C.L., Ma Y.L. and Lee E.H.Y.*
Serum- and glucocorticoid-inducible kinase 1 enhances zif268 expression through the mediation of SRF and CREB1 associated with spatial memory formation.
J. Neurochem. 105(3), 820-832 (2008)
[JCR]
[WOS]
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