Dr. Chen, Yuan-Tsong

Corresponding Research Fellow
Academician, Academia Sinica
  • 02-27899081 (Lab) (Room No: N807)
  • 02-27899085 (Fax)
Specialty:
  • Human Genetics
  • Genomic Medicine
Education and Positions:

  • M.D., Ph.D. Columbia University

Highlight Detail
...

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome.

Dr. Chen, Yuan-Tsong
J Allergy Clin Immunol., Sep 14, 2011

Stevens-Johnson syndrome (SJS) and its related disease, toxic epidermal necrolysis (TEN), are life-threatening drug hypersensitivities with robust immune responses to drugs. Despite the strong HLA predisposition to drug hypersensitivities, such as HLA-B∗1502 to carbamazepine (CBZ)-induced SJS/TEN, it remains unknown whether particular T-cell receptors (TCRs) participate in recognition of small drug/peptide-HLA complexes.

Journal Link
Back to Dr. Chern, Yijuang's Lab