Dr. Chen, Yuan-Tsong 陳垣崇 博士

List of Highlights
文件紀錄

• Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver

  Scientific Reports May 19, 2017

• Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia

  Scientific Reports Feb 23, 2017

• Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13 Deficient Mice Reveals the Importance of Palmitoylation in Hair and Skin Differentiation.

  J Invest Dermatol. Jun 29, 2015

• CXCL10/IP-10 is a Biomarker and Mediator for Kawasaki Disease.

  Circ Res. Jan 20, 2015

• Pharmacogenomics of adverse drug reactions: implementing personalized medicine.

  Hum Mol Genet. Aug 19, 2012

• Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.

  Nat Genet. May 25, 2012

• Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.

  J Allergy Clin Immunol. Feb 07, 2012

• Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome.

  J Allergy Clin Immunol. Sep 14, 2011

• Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome.

  Hum. Mol. Genet. Jul 24, 2010

• Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase.

  PLoS Genet. Jun 10, 2010

• A Genome-Wide Association Study Identifies Susceptibility Variants for Type 2 Diabetes in Han Chinese

  PLoS Genetics Feb 19, 2010

• Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data.

  NEJM. Feb 19, 2009

• Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis.

  Nature Medicine. Nov 23, 2008

• Mutations in the SLC2A10 gene cause arterial abnormalities in mice

  Cardiovascular Research. Nov 21, 2008

• Prospective Study of Warfarin Dosage Requirements Based on CYP2C9 and VKORC1 Genotypes.

  Clinical Pharmacology and Therapeutics. Jan 09, 2008

• HLA-B *1502-bound peptides: Implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.

  J Allergy Clin Immunol. Aug 11, 2007

• ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein ß-subunit.

  Human Molecular Genetics. Nov 20, 2006

• Long contiguous stretches of homozygosity in the human genome.

  Human Mutation. Sep 05, 2006

• A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

  Human Molecular Genetics. May 11, 2005

• HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol.

  PNAS. Mar 15, 2005