Dr. Tang, Tang K. 's publons link picture

Dr. Tang, Tang K.

Vice President, Academia Sinica
Distinguished Research Fellow
Academician, Academia Sinica
  • 02-27899156(lab) (Lab) (Room No: 301)
  • 02-26523901(o)
  • 02-27829143 (Fax)

Specialty:
  • Centrosome and Cilia Biogenesis
  • Mitosis
  • Neural Stem Cell Division

Education and Positions:
  • Ph.D. Human Genetics, Yale University


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Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly.

Dr. Tang, Tang K.
EMBO J., Mar 19, 2013

Centrioles are cylindrical structures that are usually composed of nine triplets of microtubules (MTs) organized around a cartwheel-shaped structure. Recent studies have proposed a structural model of the SAS-6-based cartwheel, yet we do not know the molecular detail of how the cartwheel participates in centriolar MT assembly.