HIGHLIGHT
重要成果
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- Detection and Classification of Cardiac Arrhythmias by a Challenge-Best Deep Learning Neural Network Model
- iScience, Mar 27, 2020
- Electrocardiograms (ECGs) are widely used to clinically detect cardiac arrhythmias (CAs). They are also being used to develop computer-assis ......
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- Risk stratification for lung adenocarcinoma on EGFR and TP53 mutation status, chemotherapy, and PD‐L1 immunotherapy
- Cancer Medicine, Aug 13, 2019
- The overall survival rates for lung cancer remain unsatisfactorily low, even for patients with biomarkers for which target therapies or immu ......
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- A proteome view of structural, functional, and taxonomic characteristics of major protein domain clusters
- Scientific Reports, Oct 27, 2017
- Proteome-scale bioinformatics research is increasingly conducted as the number of completely sequenced genomes increases, but analysis of pr ......
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- Identification of Entry Factors Involved in Hepatitis C Virus Infection Based on Host-Mimicking Short Linear Motifs
- PLOS Computational Biology, Jan 27, 2017
- Host factors that facilitate viral entry into cells can, in principle, be identified from a virus-host protein interaction network, but for ......
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- Proteins with highly evolvable domain architectures are non-essential but highly retained.
- Mol Biol Evol., Jan 14, 2016
- The functions of proteins are usually determined by domains, and the sequential order in which domains are connected to make up a protein ch ......
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- LISE: a server using ligand-interacting and site-enriched protein triangles for prediction of ligand-binding sites.
- Nucl. Acids Res., Apr 22, 2013
- LISE is a web server for a novel method for predicting small molecule binding sites on proteins. It differs from a number of servers current ......
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- A Critical Assessment of Information-guided Protein-protein Docking Predictions.
- Mol Cell Proteomics., Dec 13, 2012
- The structures of protein complexes are increasingly predicted by protein-protein docking (PPD) using ambiguous interaction data to help gui ......
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- OPAAS: a web server for optimal, permuted, and other alternative alignments of protein structures.
- Nucleic Acids Research., Mar 31, 2006
- The large number of experimentally determined protein 3D structures is a rich resource for studying protein function and evolution, and p ......
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