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  • +886-2-2789-9043 (Lab) (Room No: N117)
  • +886-2-2652-3031 (Office)
  • +886-2-2788-7641 (Fax)

  • Computational Biophysics
  • Computational Chemistry
  • Bioinformatics

Education and Positions:
  • 1984, Ph.D. in Chemical Physics, University of Minnesota, Minneapolis

    1979, B.S. in Chemistry, Royal Holloway College, London University


Highlight Detail

Importance of Metal Hydration on the Selectivity of Mg2+ vs. Ca2+ in Magnesium Ion Channels.

Dr. Lim, Carmay
J Am Chem Soc., Oct 02, 2013

Magnesium ion channels and transporters regulate the cellular concentrations of Mg2+, which must be tightly controlled as imbalances have been associated with diseases such as osteoporosis, diabetes, and high blood pressure in humans. They allow the "native" Mg2+ to be transported against a high background concentration of its major competitor, Ca2+. Their selectivity filters (the narrowest part of the open pore) control metal ion selectivity.