Dr. Lim, Carmay
Emeritus Research Fellow
- +886-2-2789-9043 (Lab) (Room No: N117)
- +886-2-2652-3031 (Office)
- +886-2-2788-7641 (Fax)
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Specialty:
- Computational Biophysics
- Computational Chemistry
- Bioinformatics
Education and Positions:
1984, Ph.D. in Chemical Physics, University of Minnesota, Minneapolis
1979, B.S. in Chemistry, Royal Holloway College, London University
Highlight Detail
Importance of Metal Hydration on the Selectivity of Mg2+ vs. Ca2+ in Magnesium Ion Channels.
Dr. Lim, Carmay
J Am Chem Soc., Oct 02, 2013Magnesium ion channels and transporters regulate the cellular concentrations of Mg2+, which must be tightly controlled as imbalances have been associated with diseases such as osteoporosis, diabetes, and high blood pressure in humans. They allow the "native" Mg2+ to be transported against a high background concentration of its major competitor, Ca2+. Their selectivity filters (the narrowest part of the open pore) control metal ion selectivity.