Dr. Shieh, Sheau-Yann 's publons link picture


  • 02-26523916 (Lab) (Room No: N347)
  • 02-27829143 (Fax)

  • Cancer Cell Biology
  • Cell Cycle Signaling

Education and Positions:
  • Ph.D. Baylor College of Medicine Post-doc:Columbia University

Dr. Shieh, Sheau-Yann 's

期刊 36 專書 2

  1. Chowdhury MAN, Wang SW, Suen CS, Hwang MJ, Hsueh YA, Shieh SY JAK2-CHK2 signaling safeguards the integrity of the mitotic spindle assembly checkpoint and genome stability. Cell death & disease 13(7), 619 (2022) [JCR] [WOS]
  2. Yu-Che Cheng, Sheau-Yann Shieh* Determination of CHK1 Cellular Localization by Immunofluorescence Microscopy Cell Cycle Checkpoints. Methods in Molecular Biology Vol. 2267 1-6 (2021-01) [JCR] [WOS] Book
  3. Cheng YC, Chiang HY, Cheng SJ, Chang HW, Li YJ, (Shieh SY)* Loss of the tumor suppressor BTG3 drives a pro-angiogenic tumor microenvironment through HIF-1 activation CELL DEATH & DISEASE 11(12), 1046 (2020-12) [JCR] [WOS]
  4. Hsu PC, Gopinath RK, Hsueh YA, Shieh SY CHK2-mediated regulation of PARP1 in oxidative DNA damage response. Oncogene 38(8), 1166–1182 (2019-02) [JCR] [WOS]
  5. Cheng YC, Shieh SY Deubiquitinating enzyme USP3 controls CHK1 chromatin association and activation. Proceedings of the National Academy of Sciences of the United States of America 115(21), 5546-5551 (2018) [JCR] [WOS]
  6. Chang CH, Kuo CJ, Ito T, Su YY, Jiang ST, Chiu MH, Lin YH, Nist A, Mernberger M, Stiewe T, Ito S, Wakamatsu K, Hsueh YA, Shieh SY, Snir-Alkalay I, Ben-Neriah Y CK1alpha ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation. Proceedings of the National Academy of Sciences of the United States of America 114(38), E8035-E8044 (2017) [JCR] [WOS]
  7. Yu ZC, Huang YF, Shieh SY Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation. Nucleic acids research 44(3), 1133-1150 (2016) [JCR] [WOS]
  8. Cheng YC, Chen PH, Chiang HY, Suen CS, Hwang MJ, Lin TY, Yang HC, Lin WC, Lai PL, Shieh SY Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT. Cell Death & Disease 6, e1584 (2015) [JCR] [WOS]
  9. Yeh CW, Yu ZC, Chen PH, Cheng YC, Shieh SY Phosphorylation at Threonine 288 by Cell Cycle Checkpoint Kinase 2 (CHK2) Controls Human Monopolar Spindle 1 (Mps1) Kinetochore Localization. The Journal of biological chemistry 289(22), 15319-15327 (2014) [JCR] [WOS]
  10. Cheng YC, Lin TY, Shieh SY Candidate tumor suppressor BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and activation of the checkpoint kinase CHK1. Proceedings of the National Academy of Sciences of the United States of America 110(15), 5993-5998 (2013) [JCR] [WOS]