Dr. Shyu, Bai Chuang 's publons link picture

Dr. Shyu, Bai Chuang

Adjunct Research Fellow
  • 02-27899124 (Lab) (Room No: N327)
  • 02-27829224 (Fax)

  1. Neurophysiology
  2. Electrophysiology
  3. Neuroimaging
  4. Pain

Education and Positions:
  • Ph.D. Goteborg Univ., Sweden

The central processes in the medial pain system involved in emotional responses to acute and chronic pain remain largely unresolved. In the medial pain system, high threshold afferents from somatic regions have been shown to access neurons in the medial thalamus (MT) and anterior cingulate cortex (ACC). Our long-term research objective is to investigate the nociceptive mechanism underlying the affective/emotional aspect of acute and chronic pain conveyed by the medial pain system. Recently we focused our attention to investigate the neuronal mechanisms underlying the central post stroke pain.


During the course of the studying of the thalamocingulate network activities, we developed a novel technique to prepare brain slice which contains intact thalamocingulate pathway. This preparation allows us to study the cellular mechanism underlying the information transmission in thalamocingulate circuitry in vitro. We also found that spontaneous seizure-like activities could be induced in this slice preparation. Thus it provides us a unique opportunity to study the cellular mechanism underlying the cingulate epilepsy. We thus develop another direction in epileptic research. The aims of our research in epileptic research were addressed to following issues: Thalamic modulation of cingulate epilepsy, gap junctions involved in the modulation of cingulate epilepsy, modulation of the direct current field stimulation and the cortical seizure regulated by optical stimulation of reticular thalamic nucleus. 

Our Team
Team photo

  1. Ou Chen Yin, Yu Ying Hao, Wu Chi-Wen, Kozłowska Anna, Shyu Bai-Chung, Huang Andrew Chih Wei Neuronal activity of the medial prefrontal cortex, nucleus accumbens, and basolateral amygdala in conditioned taste aversion and conditioned place preference induced by different doses of morphine administrations in rats Frontiers in Pharmacology 14, ePub (2023-01-24) [JCR] [WOS]
  2. Pei-Chun Chou, Chih-Min Liu, Ching-Hui Weng, Kai-Chien Yang, Mei-Ling Cheng, Yuh-Charn Lin, Ruey-Bing Yang, Bai-Chuang Shyu, Song-Kun Shyue, Jin-Dian Liu, Shih-Pin Chen, Michael Hsiao and Yu-Feng Hu Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes CIRCULATION RESEARCH 131(1), 6-20 (2022-05-25) [JCR] [WOS]
  3. Hsiang-Chin Lu, Wei-Jen Chang, Andrew Chih Wei Huang, Bai Chuang Shyu Detection of pentylenetetrazol-induced seizure activity in the 19-21 Hz beta range using a magnetic coil induction method. FRONTIERS IN BIOSCIENCE-LANDMARK 27(3), 81 (2022-05-05) [JCR] [WOS]
  4. Tavleen Kaur, Hsi-Chien Shih, Andrew Chih Wei Huang, Bai-Chuang Shyu Modulation of melatonin to the thalamic lesion-induced pain and comorbid sleep disturbance in the animal model of the central post-stroke hemorrhage. MOLECULAR PAIN 18, doi: 10.1177/17448069221127180 (2022-04-18) [JCR] [WOS]
  5. Wu CW, Ou CY, Yu YH, Yu YC, Shyu BC, Huang ACW. Involvement of the ventral tegmental area but not periaqueductal gray matter in the paradoxical rewarding and aversive effects of morphine. Behavioral Neuroscience 135(6), 762-770 (2021-12) [JCR] [WOS]
  6. Chin-Tsang Yang, Bai-Chuang Shyu, Yeong-Ray Wen. A brain recording system to study the effect of pulsed radiofrequency spinal cord stimulation on neuropathic pain. 2021 Taiwan Society for Neuroscience (TSfN) (2021-09) [JCR] [WOS]
  7. Hsi-Chien Shih, Tweety Kuan and Bai-Chung Shyu. Central Post-Stroke Pain was Suspended by Knockout of P2X7 Gene: A Mice Model Research. 2021 Taiwan Society for Neuroscience (TSfN) (2021-09) [JCR] [WOS]
  8. Tavleen Kaur, Bai-Chuang Shyu Neuromodulatory effect of exogenous melatonin on Central Post Stroke Pain in rodents. 2021 Taiwan Society for Neuroscience (TSfN) (2021-09) [JCR] [WOS]
  9. Chang SH, Shaw FZ, Shyu BC. The Temporal Profiling and Modulation of Traumatic Stress Related Fears in a Rat Model of Post-Traumatic Stress Disorder. ENCODS 2021 - European Neuroscience Conference by Doctoral Students (Virtual Forum) (2021-06) [JCR] [WOS]
  10. Shao-Han Chang, Ying Hao Yu, Alan He, Chen Yin Ou, Bai Chuang Shyu, Andrew Chih Wei Huang. BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model. Behavioral Neurology Volume 2021, 1-13 (2021-05-09) [JCR] [WOS]

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