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Dr. Hu, Che-Ming (Jack)

Associate Research Fellow
  • 2652-3089 (Lab) (Room No: N534)
  • 2788-7641 (Fax)
Specialty:

Biomaterials and Nanotechnology for Drug and Vaccine Development

Education and Positions:

  • B.S. University of California, Berkeley (Biomedical Engineering)

    Ph.D. University of California, San Diego (Bioengineering)

Advances in bionanotechnology and cargo-carrying nanocarriers enable existing therapeutics to be reformulated to attain higher potency and safety. Nanotechnology in medicine has shown tremendous value in drug delivery and vaccine preparations, where pharmacokinetics and immune activation can be finely tuned via rational nanomaterials engineering. The research focus of the laboratory is to develop novel therapeutic nanomaterials with an emphasis toward clinical translation. By examining and tackling the interface between materials and biology, we seek to adopt an engineering approach to improve treatments for major diseases including cardiovascular disease, cancer, and infectious disease.

Our Team
Team photo

Journal 72 Book 0

  1. Liu Cheng-Hao, Pan Yi-Chung, Lim See-Khai, Mou Chung-Yuan, 「Hu Che-Ming Jack*」, Mou Kurt Yun Combinatorial leaky probiotic for anticancer immunopotentiation and tumor eradication. Cell Reports Medicine 5(11), 101793 (2024-11) [JCR] [WOS]
  2. Lin Chi-Long, Fang Zih-Syun, Hsu Chung-Yao, Liu Yu-Han, Lin Jung-Chen, Yao Bing-Yu, Li Fu-An, Yen Shin-Chwen Bruce, Chang Yuan-Chih,「Hu Che-Ming J*」 Rapid plasma membrane isolation via intracellular polymerization-mediated biomolecular confinement. Acta Biomaterialia 173, 325-335 (2024-01-01) [JCR] [WOS]
  3. Lim S-K, Lin W-C, Huang S-W, Pan Y-C, Hu C-W, Mou C-Y, 「Hu C-M*」, Mou K Bacteria colonization in tumor microenvironment creates a favorable niche for immunogenic chemotherapy. EMBO MOLECULAR MEDICINE (2024) [JCR] [WOS]
  4. Chiu CT, Tsai HH, Chen JY, 「Hu CJ」, Chen HW* An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity.. International journal of nanomedicine 19, 7201-7214 (2024) [JCR] [WOS]
  5. Wu J, Roesger S, Jones N, 「Hu CJ」, Li SD* Cell-penetrating peptides for transmucosal delivery of proteins.. Journal of controlled release : official journal of the Controlled Release Society 366, 864-878 (2024) [JCR] [WOS]
  6. Baghdasaryan O, Contreras-Llano LE, Khan S, Wang A, 「Hu CJ*」, Tan C* Fabrication of cyborg bacterial cells as living cell-material hybrids using intracellular hydrogelation.. Nature protocols 19(12), 3613-3639 (2024) [JCR] [WOS]
  7. Yu YA, Lien WJ, Lin WC, Pan YC, Huang SW, Mou CY, 「Hu CJ*」, Mou KY High-Affinity Superantigen-Based Trifunctional Immune Cell Engager Synergizes NK and T Cell Activation for Tumor Suppression.. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11(33), e2310204 (2024) [JCR] [WOS]
  8. Huang SW, Lim SK, Yu YA, Pan YC, Lien WJ, Mou CY*, 「 Hu CJ*」, Mou KY Overcoming the nutritional immunity by engineering iron-scavenging bacteria for cancer therapy.. eLife 12, RP90798 (2024) [JCR] [WOS]
  9. Baghdasaryan Ofelya, Khan Shahid, Lin Jung-Chen, Lee-Kin Jared, Hsu Chung-Yao, 「Hu Che-Ming Jack*」, Tan Cheemeng* Synthetic control of living cells by intracellular polymerization. Trends in Biotechnology (2023-09-01) [JCR] [WOS]
  10. Francisco Jamie, Guan Jin, Zhang Yu, Nakada Yasuki, Mareedu Satvik, Sung Eun-Ah, 「Hu Che-Ming」, Oka Shinichi, Zhai Peiyong, Sadoshima Junichi, Del Re Dominic P*. Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress. Journal of Molecular and Cellular Cardiology 181, 1-14 (2023-08-01) [JCR] [WOS]
- More Publications-

- POSTDOC -
Lin, Leon
Lin, Leon
Lin, jung-Chen
Lin, jung-Chen
Liu, Seny
Liu, Seny
Lin, Jeffrey
Lin, Jeffrey
- RESEARCH ASSOCIATES -
Yao, Bing-Yu
Yao, Bing-Yu
Hsu, Chung-Yao
Hsu, Chung-Yao
- STUDENTS -
Chattopadhyay, Saborni
Chattopadhyay, Saborni
Tsai, Sherry
Tsai, Sherry
Fang, Angela
Fang, Angela
Yang, KJ
Yang, KJ
- ALUMNI -
Chien, Grace
Chien, Grace
Tsai, David
Tsai, David
Huang, Christine
Huang, Christine
Hsieh, Cheryl
Hsieh, Cheryl
Hsieh, Ken
Hsieh, Ken
Yang, Amber
Yang, Amber
Chen, Rita
Chen, Rita
Hsieh, JX
Hsieh, JX

2019    Excellent Young Investigator Award—Taiwan Biomaterials and Controlled Releases Society

2017    Futuristic Breakthrough Technology Award by Ministry of Science and Technology.

2016    4th Annual Excellence in Creativity Award for Young Scholar

2016    Member of the Global Young Academy
2016    Recipient of the Academia Sinica Career Development Award 
2014    Selected participant of the 64th Meeting of Nobel Laureates
2013    Chancellor’s Postdoctoral Scholar Award, UCSD 2013
2011    Siebel Scholar, Class of 2012 
2010    Best poster award at the 8th NanoDDS
2004    Guidant Undergraduate Research Fellowship