Dr. Chen, Huan-Yuan

Associate Research Scientist
  • 02-2652-3940 (Lab) (Room No: N433)
  • 02-2652-3945
  • 02-2652-3942 (Fax)

  • 發炎核心設施負責人
  • Galectins
  • Skin Inflammation

Education and Positions:
  • Ph.D. National Tsing Hua University

Our laboratory aims to promote research in inflammation and glycomedicine by 1) coordinating the Inflammation forum, 2) providing reagents/services including those listed under “Service”, and 3) assisting in establishing the IBMS glycobiology core. 

Our research is focused on 1) investigation of the functions of galectins in skin inflammation, such as atopic dermatitis, contact dermatitis, and psoriasis, and 2) investigation of the roles of galectin-3 in Alix-mediated functions, such as retrovirus budding and exosome secretion. 

Journal 30 Book 0

  1. Wang SF, Tseng SP, Loh EW, Wang WH, Li MC, Chen KH, Tsai WC, Lee YM, Chen HY, Liu FT, Arthur Chen YM, Huang JC Generation and characterization of new monoclonal antibodies against swine origin 2009 influenza A (H1N1) virus and evaluation of their prophylactic and therapeutic efficacy in a mouse model. Developmental and comparative immunology 67, 8-17 (2017) [JCR] [WOS]
  2. Chen HL, Chiang PC, Lo CH, Lo YH, Hsu DK, Chen HY, Liu FT Galectin-7 Regulates Keratinocyte Proliferation and Differentiation through JNK-miR-203-p63 Signaling. The Journal of investigative dermatology 136(1), 182-191 (2016-01) [JCR] [WOS]
  3. Huang WC, Chen HL, Chen HY, Peng KP, Lee Y, Huang LM, Chang LY, Liu FT Galectin-3 and Its Genetic Variation rs4644 Modulate Enterovirus 71 Infection. PloS one 11(12), e0168627 (2016) [JCR] [WOS]
  4. Tian J, Yang G, Chen HY, Hsu DK, Tomilov A, Olson KA, Dehnad A, Fish SR, Cortopassi G, Zhao B, Liu FT, Gershwin ME, Torok NJ, Jiang JX Galectin-3 regulates inflammasome activation in cholestatic liver injury. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 30(12), 4202-4213 (2016) [JCR] [WOS]
  5. Chen HY, Chiang DM, Lin ZJ, Hsieh CC, Yin GC, Weng IC, Guttermann P, Werner S, Henzler K, Schneider G, Lai LJ, Liu FT Nanoimaging granule dynamics and subcellular structures in activated mast cells using soft X-ray tomography. Scientific reports 6, 34879 (2016) [JCR] [WOS]
  6. Li JR, Ross SS, Liu Y, Liu YX, Wang KH, Chen HY, Liu FT, Laurence TA, Liu GY Engineered Nanostructures of Haptens Lead to Unexpected Formation of Membrane Nanotubes Connecting Rat Basophilic Leukemia Cells. ACS nano 9(7), 6738-6746 (2015) [JCR] [WOS]
  7. Chen HY, Weng IC, Li CS, Wan L, Liu FT Examination of galectins in phagocytosis. Methods in molecular biology (Clifton, N.J.) 1207, 201-213 (2015) [JCR] [WOS]
  8. Lai CY, Yeh DW, Lu CH, Liu YL, Huang LR, Kao CY, Chen HY, Huang CY, Chang CH, Luo Y, Xiang R, Chuang TH Identification of Thiostrepton as a Novel Inhibitor for Psoriasis-like Inflammation Induced by TLR7-9. Journal of immunology 195(8), 3912-3921 (2015) [JCR] [WOS]
  9. Wang SF, Tsao CH, Lin YT, Hsu DK, Chiang ML, Lo CH, Chien FC, Chen P, Arthur Chen YM, Chen HY, Liu FT Galectin-3 promotes HIV-1 budding via association with Alix and Gag p6. Glycobiology 24(11), 1022-1035 (2014) [JCR] [WOS]
  10. Chen HY, Weng IC, Hong MH, Liu FT Galectins as bacterial sensors in the host innate response. Current Opinion in Microbiology 17C, 75-81 (2014) [JCR] [WOS]