• Jul 13, 2023
• Jul 13, 2023
• Jun 30, 2023 Welcome to our new members!

Journal 19 Book 0

1. He C, Xing X, Chen HY, Gao M, Shi J, Xiang B, Xiao X, Sun Y, Yu H, Xu G, Yao Y, Xie Z, Xing Y, Budiarto BR, Chen SY, Gao Y, (Lee YR)*, Zhang J* UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity.. Molecular cell 84(6), 1120-1138.e8 (2024) [JCR] [WOS]
2. Xiao X, Shi J, He C, Bu X, Sun Y, Gao M, Xiang B, Xiong W, Dai P, Mao Q, Xing X, Yao Y, Yu H, Xu G, Li S, Ren Y, Chen B, Jiang C, Meng G, (Lee YR), Wei W, Freeman GJ, Xie C, Zhang J ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.. Nature communications 14(1), 2859 (2023) [JCR] [WOS]
3. Zhang T, Xu D, Trefts E, Lv M, Inuzuka H, Song G, Liu M, Lu J, Liu J, Chu C, Wang M, Wang H, Meng H, Liu H, Zhuang Y, Xie X, Dang F, Guan D, Men Y, Jiang S, Jiang C, Dai X, Liu J, Wang Z, Yan P, Wang J, Tu Z, Babuta M, Erickson E, Hillis AL, Dibble CC, Asara JM, Szabo G, Sicinski P, Miao J, (Lee YR), Pan L, Shaw RJ, Yuan J, Wei W Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1.. Science (New York, N.Y.) 380(6652), 1372-1380 (2023) [JCR] [WOS]
4. Zhang T, Xu D, Liu J, Wang M, Duan LJ, Liu M, Meng H, Zhuang Y, Wang H, Wang Y, Lv M, Zhang Z, Hu J, Shi L, Guo R, Xie X, Liu H, Erickson E, Wang Y, Yu W, Dang F, Guan D, Jiang C, Dai X, Inuzuka H, Yan P, Wang J, Babuta M, Lian G, Tu Z, Miao J, Szabo G, Fong GH, Karnoub AE, (Lee YR), Pan L, Kaelin WG Jr, Yuan J, Wei W Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.. Nature cell biology Jul 3., Jul 3.-Jul 3. (2023) [JCR] [WOS]
5. Lee JD, Paulo JA, Posey RR, Mugoni V, Kong NR, Cheloni G, (Lee YR), Slack FJ, Tenen DG, Clohessy JG, Gygi SP, Pandolfi PP Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia.. Nature methods 18(3), 293–302 (2021) [JCR] [WOS]
6. Kishikawa T, Higuchi H, Wang L, Panch N, Maymi V, Best S, Lee S, Notoya G, Toker A, Matesic LE, Wulf GM, Wei W, Otsuka M, Koike K, Clohessy JG, Lee YR, Pandolfi PP WWP1 inactivation enhances efficacy of PI3K inhibitors while suppressing their toxicities in breast cancer models.. The Journal of clinical investigation 131(24), e140436-e140436 (2021) [JCR] [WOS]
7. Lee YR, Pandolfi PP PTEN Mouse Models of Cancer Initiation and Progression.. Cold Spring Harbor perspectives in medicine 10(2), a037283-a037283 (2020) [JCR] [WOS]
8. Lee YR, Yehia L, Kishikawa T, Ni Y, Leach B, Zhang J, Panch N, Liu J, Wei W, Eng C, Pandolfi PP WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition.. The New England journal of medicine 382(22), 2103-2116 (2020) [JCR] [WOS]
9. Zhang J#, Lee YR#, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. #Co-first author PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.. CANCER DISCOVERY 9(9), 1306-1323 (2019) [JCR] [WOS]
10. Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.. Science (New York, N.Y.) 364(6441), aau0159-aau0159 (2019) [JCR] [WOS]

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• 誠徵: 約聘研究助理 1名
• 誠徵: 博士後研究 1名
• 誠徵: 約聘研究助理 1名

 

• Li Foundation Heritage Prize for "Excellence in Creativity" (2021)
• Academia Sinica Career Development Award (2021)
• Special outstanding talent award from the Ministry of Science and Technology (延攬特殊優秀人才）
• Investigator Fellowship from Academia Sinica (新聘學術研究獎）
• DOD Post-Doc Training Award (W81XWH-16-1-0249), USA, 2016
• Postdoctoral Research Abroad Program Fellowship, Taiwan National Science Council (NSC) (2014-2016)
• The Excellent Research Paper Award from Dr. Tien-Te Lee’s Biomedical Foundation (2011) (李天德傑出論文獎）
• Poster Presentation Distinguished Achievement Award, the 19th Symposium on Recent Advances in Cellular and Molecular Biology (2011)
• Poster Presentation Distinguished Achievement Award, the 20th Federation of Asia and Oceanian Biochemists and Molecular Biologists (FAOBMB) conferences (2008)