Dr. Chen, Yuan-Tsong

Corresponding Research Fellow
Academician, Academia Sinica
  • 02-27899081 (Lab) (Room No: N807)
  • 02-27899085 (Fax)

  • Human Genetics
  • Genomic Medicine

Education and Positions:
  • M.D., Ph.D. Columbia University

Highlight Detail

HLA-B *1502-bound peptides: Implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.

Dr. Chen, Yuan-Tsong
J Allergy Clin Immunol., Aug 11, 2007

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can involve MHC-restricted presentation of a drug or its metabolites for T-cell activation. HLA-B1502 tightly associated with carbamazepine (CBZ) induced these conditions in a Han Chinese population.