Dr. Shyu, Bai Chuang 's publons link picture

Dr. Shyu, Bai Chuang

Adjunct Research Fellow
  • 02-27899124 (Lab) (Room No: N327)
  • 02-27829224 (Fax)

  1. Neurophysiology
  2. Electrophysiology
  3. Neuroimaging
  4. Pain

Education and Positions:
  • Ph.D. Goteborg Univ., Sweden

Highlight Detail

Targeting P2X7 receptor for the treatment of central post-stroke pain in a rodent model.

Dr. Shyu, Bai Chuang
Neurobiol Dis., May 30, 2015

Stroke is a leading cause of death and disability in industrialized countries. Approximately 8-14% of stroke survivors suffer from central post-stroke pain (CPSP) when hemorrhagic stroke occurs in lateral thalamic regions, which severely affects their quality of life. Because the mechanisms of CPSP are not well understood, effective treatments have not been developed. In the present study, we tested the hypothesis that persistent CPSP is caused by P2X7 receptor activation after brain tissue damage and subsequent elevations in inflammatory cytokines.