Dr. Yang, Pan-Chyr
Corresponding Research Fellow
Academician, Academia Sinica
- 02-27899149 (Lab) (Room No: 511)
- 02-27858594 (Fax)
-
Specialty:
- Cell and Molecular Biology
- Cancer genomics
Education and Positions:
M.D., Ph.D. National Taiwan University
Highlight Detail
Extracellular delivery of modified oligonucleotide and superparamagnetic iron oxide nanoparticles from a degradable hydrogel triggered by tumor acidosis.
Dr. Yang, Pan-Chyr
Biomaterials., Mar 08, 2013Chemically modified antisense RNA oligonucleotides (antagomir) offer promise for cancer therapies but suffer from poor therapeutic effect after systemic administration. Chemical modification or loading in degradable hydrogels can offer improvements in the accuracy and efficacy for sustained delivery at specific sites. In our approach