Dr. Hsieh, Patrick Ching-Ho
Distinguished Research Fellow
Division Chief
- 02-27899170 (Lab) (Room No: N417)
- 02-27858594 (Fax)
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Specialty:
- Stem cells and regenerative medicine
- Nanoscience and nanomedicine
- Translational Research
Education and Positions:
M.D. Kaohsiung Medical College
Ph.D. University of Washington, Seattle (Bioengineering)
Highlight Detail
Functionalized Nanoparticles Provide Early Cardioprotection after Acute Myocardial Infarction.
Dr. Hsieh, Patrick Ching-Ho
J Control Release, May 09, 2013Recent developments in nanotechnology have created considerable potential toward diagnosis and cancer therapy. In contrast, the use of nanotechnology in tissue repair or regeneration remains largely unexplored. We hypothesized that intramyocardial injection of insulin-like growth factor (IGF)-1-complexed poly (D,L-lactide-co-glycolide) (PLGA) nanoparticles (PLGA-IGF-1 NPs) increases IGF-1 retention, induces Akt phosphorylation, and provides early cardioprotection after acute myocardial infarction (MI).