Dr. Lee, Eminy H.Y. 's publons link picture

Dr. Lee, Eminy H.Y.

Distinguished Research Fellow
Division Chief
  • 02-27899125 (Lab) (Room No: 308)
  • 02-27829224 (Fax)
Specialty:
  • Pathogenesis of and Neuroprotection against Alzheimer's Disease
  • Molecular Mechanism of Mammalian Long-Term Memory Formation
Education and Positions:

Ph.D. Univ. of California, San Diego

Dr. Lee, Eminy H.Y. 's
Publications

Journal 96 Book 0

  1. Cheng K.M., Hsu W.L., Ma Y.L., Liu Y.C. and Lee E.H.Y.* Novel role of NCoR1 in impairing spatial memory through the mediation of a novel interacting protein DEC2.. CELLULAR AND MOLECULAR LIFE SCIENCES 81:273, 1-30 (2024-06) [JCR] [WOS]
  2. W.L. Hsu, Y.L. Ma, Y.C. Chen, Y.C. Liu, K.M. Cheng, Eminy H. Y. Lee Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN. PLOS ONE 18(4), e0283908-e0283908 (2023-04) [JCR] [WOS]
  3. Liu Y.C., Hsu W.L., Ma Y.L. and Lee E.H.Y.* Melatonin induction of APP intracellular domain 50 SUMOylation alleviates Alzheimer\'s disease through enhanced transcriptional activation and Abeta degradation.. Molecular Therapy 29, 376-395 (2021-01) [JCR] [WOS]
  4. Tao C.C., Cheng K.M., Ma Y.L., Hsu W.L., Chen Y.C., Fuh J.L., Lee W.J., Chao C.C. and Lee E.H.Y.* Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease.. Cell Death and Differentiation 27, 192-209 (2020-05) [JCR] [WOS]
  5. Hsu W.L., Ma Y.L., Liu Y.C., Tai D.J.C. and Lee E.H.Y.* Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome.. Scientific Reports 10, 1074 (2020-02) [JCR] [WOS]
  6. Liu S.Y., Ma Y.L., Hsu W.L., Chiou H.Y. and Lee E.H.Y.* Protein inhibitor of activated STAT1 Ser503 phosphorylation‐mediated Elk‐1 SUMOylation promotes neuronal survival in APP/PS1 mice.. British Journal of Pharmacology 176, 1793-1810 (2019-06) [JCR] [WOS]
  7. Hsu W.L., Ma Y.L., Liu Y.C. and Lee E.H.Y.* Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2.. BMC Biology 15, 112, doi 10.1186/s12 (2017-11) [JCR] [WOS]
  8. Chen Y.C., Ma Y.L., Lin C.H., Cheng S.J., Hsu W.L. and Lee E.H.Y.* Galectin-3 negatively regulates hippocampus-dependent memory formation through inhibition of integrin signaling and galectin-3 phosphorylation.. Frontiers in Molecular Neuroscience doi: 10.3389/fnmol.2017.00217,10, 1-15 (2017-07) [JCR] [WOS]
  9. Tao C.C., Hsu W.L., Ma Y.L., Cheng S.J. and Lee E.H.Y.* Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Abeta toxicity in a mouse model of Alzheimer's disease.. Cell Death and Differentiation 24, 597-614 (2017-04) [JCR] [WOS]
  10. Tai J.C.§, Liu Y.C.§, Hsu W.L.§, Ma Y.L., Cheng S.J., Liu S.Y. and Lee E.H.Y.* MeCP2 SUMOylation rescues Mecp2 mutant-induced behavioral deficits in a mouse model of Rett syndrome.. Nature Communications 7, 10552 (2016-02) [JCR] [WOS]
Dr. Chern, Yijuang's Lab