Dr. Lee, Eminy H.Y. 's publons link picture

Dr. Lee, Eminy H.Y.

Distinguished Research Fellow
  • 02-27899125 (Lab) (Room No: 308)
  • 02-27829224 (Fax)
Specialty:
  • Pathogenesis of and Neuroprotection against Alzheimer's Disease
  • Molecular Mechanism of Mammalian Long-Term Memory Formation
Education and Positions:

  • Ph.D. Univ. of California, San Diego

Dr. Lee, Eminy H.Y. 's
Publications

  1. Liu Y.C., Hsu W.L., Ma Y.L. and Lee E.H.Y.* Melatonin induction of APP intracellular domain 50 SUMOylation alleviates Alzheimer\'s disease through enhanced transcriptional activation and Abeta degradation Molecular Therapy 29, 376-395 (2021-01) [JCR] [WOS]
  2. Hsu W.L., Ma Y.L., Liu Y.C., Tai D.J.C. and Lee E.H.Y.* Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome Scientific Reports 10, 1074 (2020-02) [JCR] [WOS]
  3. Tao C.C., Cheng K.M., Ma Y.L., Hsu W.L., Chen Y.C., Fuh J.L., Lee W.J., Chao C.C. and Lee E.H.Y.* Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease Cell Death and Differentiation 27(1),192-209 (2020-01) [JCR] [WOS]
  4. Liu S.Y., Ma Y.L., Hsu W.L., Chiou H.Y. and Lee E.H.Y.* Protein inhibitor of activated STAT1 Ser503 phosphorylation‐ mediated Elk‐1 SUMOylation promotes neuronal survival in APP/PS1 mice British Journal of Pharmacology 176(11),1793-1810 (2019-06) [JCR] [WOS]
  5. Hsu W.L., Ma Y.L., Liu Y.C. and Lee E.H.Y.* Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2 BMC Biology 15(1), 112. (2017-11) [JCR] [WOS]
  6. Chen Y.C., Ma Y.L., Lin C.H., Cheng S.J., Hsu W.L. and Lee E.H.Y.* Galectin-3 negatively regulates hippocampus-dependent memory formation through inhibition of integrin signaling and galectin-3 phosphorylation Frontiers in Molecular Neuroscience doi: 10.3389/fnmol.2017.00217,10, 1-15 (2017-07) [JCR] [WOS]
  7. Tao C.C., Hsu W.L., Ma Y.L., Cheng S.J. and Lee E.H.Y.* Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Abeta toxicity in a mouse model of Alzheimer's disease Cell Death and Differentiation 24, 597-614 (2017-04) [JCR] [WOS]
  8. Tai J.C.§, Liu Y.C.§, Hsu W.L.§, Ma Y.L., Cheng S.J., Liu S.Y. and Lee E.H.Y.* MeCP2 SUMOylation rescues Mecp2 mutant-induced behavioral deficits in a mouse model of Rett syndrome Nature Communications 7, 10552 (2016-02) [JCR] [WOS]
  9. Lin C.H., Liu S.Y. and Lee E.H.Y.* SUMO-modification of Akt enhances global SUMOylation and substrate SUMOylation specificity through Akt phosphorylation of Ubc9 and SUMO1 Oncogene 35, 595-607 (2016-02) [JCR] [WOS]
  10. Chen Y.C.§, Hsu W.L.§, Ma Y.L., Tai J.C. and Lee E.H.Y.* CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory J. Neuroscience 34, 9574-9589 (2014-07) [JCR] [WOS]
Dr. Chern, Yijuang's Lab