Dr. Chang, Ya-Jen 's orcid link picture Dr. Chang, Ya-Jen 's publons link picture

Dr. Chang, Ya-Jen

Research Fellow
  • 02-27899050 (Lab) (Room No: N527)
  • 02-27898594 (Fax)
Specialty:
  1. Allergy and asthma
  2. Innate immunity and mucosal immunology
  3. Immunopharmacology
Education and Positions:

  • Ph.D., Pharmacology, National Taiwan University; 

    Instructor in Pediatrics, Harvard Medical School; 

    Research Associate in Immunology, Boston Children's Hospital

Dr. Chang, Ya-Jen 's
Publications

Journal 48 Book 1

  1. Luo CH, Lai AC, Tsai CC, Chen WY, Chang YS, Chung EJ, (Chang YJ*) Staphylococcus aureus exacerbates dermal IL-33-ILC2 axis activation through evoking RIPK3/MLKL-mediated necroptosis of dry skin JCI Insight 9(6), e166821 (2024-02) [JCR] [WOS]
  2. Thio CL, (Chang YJ*) Modulation of pulmonary group 2 innate lymphoid cell function in asthma: From inflammatory mediators to environmental and metabolic factors Experimental and Molecular Medicine 10.1038, 1-13 (2023-09) [JCR] [WOS]
  3. Tsai CH, Lai AC, Lin YC, Chi PY, Chen YC, Yang YH, Chen CH, Shen SY, Hwang TL, Su MW, Hsu IL, Maitland-van der Zee AH, McGeachie MJ, Tantisira KG, (Chang YJ*), Lee YL* Neutrophil extracellular trap production and CCL4L2 expression influence corticosteroid response in asthma Science Translational Medicine 15, eadf3843 (2023-06) [JCR] [WOS]
  4. Luo CH, Lai AC*, (Chang YJ*) Butyrate inhibits Staphylococcus aureus aggravated dermal IL-33 expression and skin inflammation through histone deacetylase inhibition. Frontiers in Immunology 14, 1114699 (2023-05) [JCR] [WOS]
  5. González-Cuesta M, Lai AC, Chi PY, Hsu IL, Liu NT, Wu KC, García Fernández M, (Chang YJ*), Ortiz Mellet C* Serine-/Cysteine-Based sp2‑Iminoglycolipids as Novel TLR4 Agonists: Evaluation of Their Adjuvancy and Immunotherapeutic Properties in a Murine Model of Asthma Journal of Medicinal Chemistry (2023-03) [JCR] [WOS]
  6. Thio CL, Lai AC, Wang JC, Chi PY, Chang YL, Ting YT, Chen SY, (Chang YJ*) Identification of a PD-L1+Tim-1+ iNKT subset that protects against fine particulate matter–induced airway inflammation JCI Insight 7(23), e164157 (2022-12) [JCR] [WOS]
  7. Thio CL, Lai AC, Ting YT, Chi PY, (Chang YJ*) The ketone body β-hydroxybutyrate mitigates ILC2-driven airway inflammation by regulating mast cell function Cell Reports 40, 111437 (2022-09) [JCR] [WOS]
  8. Chung EJ, Luo CH, Thio CL, (Chang YJ*) Immunomodulatory Role of Staphylococcus aureus in Atopic Dermatitis Pathogens 11, 422-432 (2022-03) [JCR] [WOS]
  9. Li LC, Chen WY, Chen JB, Lee WC, Chang CC, Tzeng HT, Huang CC, (Chang YJ), Yang JL The AST-120 Recovers Uremic Toxin-Induced Cognitive Deficit via NLRP3 Inflammasome Pathway in Astrocytes and Microglia Biomedicines 9, 1252 (2021-09) [JCR] [WOS]
  10. He YH, Yeh MH, Chen HF, Wang TS, Wong RH, Wei YL, Huynh TK, Hu DW, Cheng FJ, Chen JY, Hu SW, Huang CC, Chen Y, Yu J, Cheng WC, Shen PC, Liu LC, Huang CH, (Chang YJ), Huang WC. ERα determines the chemoresistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions. Molecular Therapy-Nucleic Acids 25, 536-553 (2021-08) [JCR] [WOS]
Dr. Chern, Yijuang's Lab