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Dr. Cheng, Yang

Assistant Research Fellow
  • 2789-9097 (Lab) (Room No: N401)
  • 2652-3966 (Office)
Specialty:
  • Human T cell biology, virus-specific memory T cells
  • Highly multiplexed combinatorial pMHC tetramer staining
  • Single-cell multi-omics
  • T cell receptor
  • High-dimensional analysis
Education and Positions:

  • M.Sc., University College London
    Ph.D., Nanyang Technological University – A*STAR joint program
    Postdoc Fellow, Singapore Immunology Network, A*STAR
    Senior Research Scientist, Massachusetts General Hospital, Harvard Medical School

Dr. Cheng, Yang 's
Publications

Journal 19 Book 0

  1. Mattox AK, Roelands J, Saal TM, (Cheng Y), Rinchai D, Hendrickx W, Young GD, Diefenbach TJ, Berger AE, Westra WH, Bishop JA, Faquin WC, Marincola FM, Pittet MJ, Bedognetti D, Pai SI* Myeloid Cells Are Enriched in Tonsillar Crypts, Providing Insight into the Viral Tropism of Human Papillomavirus. AMERICAN JOURNAL OF PATHOLOGY 191(10), 1774-1786 (2021-10) [JCR] [WOS]
  2. (Cheng Y), Gunasegaran B, Singh HD, Dutertre CA, Loh CY, Lim JQ, Crawford JC, Lee HK, Zhang X, Lee B, Becht E, Lim WJ, Yeong J, Chan CY, Chung A, Goh BKP, Chow PKH, Chan JKY, Ginhoux F, Tai D, Chen J, Lim SG, Zhai W, Choo SP, Newell EW* Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma. IMMUNITY 54(8), 1825-1840.e7 (2021-08-10) [JCR] [WOS]
  3. Le Bert N, Gill US, Hong M, Kunasegaran K, Tan DZM, Ahmad R, (Cheng Y), Dutertre CA, Heinecke A, Rivino L, Tan A, Hansi NK, Zhang M, Xi S, Chong Y, Pflanz S, Newell EW, Kennedy PTF, Bertoletti A* Effects of Hepatitis B Surface Antigen on Virus-Specific and Global T Cells in Patients With Chronic Hepatitis B Virus infection. GASTROENTEROLOGY 159(2), 652-664 (2020-08) [JCR] [WOS]
  4. Dress RJ, Dutertre CA, Giladi A, Schlitzer A, Low I, Shadan NB, Tay A, Lum J, Kairi MFBM, Hwang YY, Becht E, (Cheng Y), Chevrier M, Larbi A, Newell EW, Amit I, Chen J, Ginhoux F* Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage. NATURE IMMUNOLOGY 20(7), 852-864 (2019-07) [JCR] [WOS]
  5. (Cheng Y), Zhu YO, Becht E, Aw P, Chen J, Poidinger M, de Sessions PF, Hibberd ML, Bertoletti A, Lim SG, Newell EW* Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection. SCIENCE IMMUNOLOGY 4(32), NA-NA (2019-02-08) [JCR] [WOS]
  6. Becht E, Simoni Y, Coustan-Smith E, Evrard M, (Cheng Y), Ng LG, Campana D, Newell EW* Reverse-engineering flow-cytometry gating strategies for phenotypic labelling and high-performance cell sorting. BIOINFORMATICS 35(2), 301-308 (2019-01-15) [JCR] [WOS]
  7. Rivino L, Le Bert N, Gill US, Kunasegaran K, (Cheng Y), Tan DZ, Becht E, Hansi NK, Foster GR, Su TH, Tseng TC, Lim SG, Kao JH, Newell EW, Kennedy PT, Bertoletti A* Hepatitis B virus-specific T cells associate with viral control upon nucleos(t)ide-analogue therapy discontinuation. JOURNAL OF CLINICAL INVESTIGATION 128(2), 668-681 (2018-02-01) [JCR] [WOS]
  8. Sumatoh HR, Teng KW, (Cheng Y), Newell EW* Optimization of mass cytometry sample cryopreservation after staining. CYTOMETRY PART A 91(1), 48-61 (2017-01) [JCR] [WOS]
  9. Newell EW* and (Cheng Y) Mass cytometry: blessed with the curse of dimensionality. NATURE IMMUNOLOGY 17(8), 890-895 (2016-07-19) [JCR] [WOS]
  10. (Cheng Y), Wong MT, van der Maaten L, Newell EW* Categorical Analysis of Human T Cell Heterogeneity with One-Dimensional Soli-Expression by Nonlinear Stochastic Embedding. JOURNAL OF IMMUNOLOGY 196(2), 924-932 (2016-01-15) [JCR] [WOS]
Dr. Chern, Yijuang's Lab