Dr. Chen, Steve S.-L.

Emeritus Research Fellow

Specialty:
  • Retrovirology
  • HCV
  • Virus-host Interactions
  • Virus Assembly and Budding

Education and Positions:
  • Ph.D., Biochemistry,  Purdue University


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Autophagy: A novel guardian of HCV against innate immune response

Dr. Chen, Steve S.-L.
Autophagy, Jan 01, 2011

Autophagy is an evolutionarily conserved process that catabolizes intracellular components and maintains cellular homeostasis. Autophagy involves the sequestration of cytoplasmic content within a double-membraned autophagosome, and the fusion of the autophagosome with a lysosome to form an autolysosome for subsequent degradation (Fig. 1A). Autophagy plays a pivotal role in various aspects of cellular responses to stresses