Dr. Chen, Chinpan 陳金榜博士 HIGHLIGHT DETAIL 重要成果詳細內容

HIGHLIGHT DETAIL
重要成果詳細內容

Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation

Nucl. Acids Res., Sep 08, 2011

Trichomonas vaginalis Myb3 transcription factor (tvMyb3) recognizes the MRE-1 promoter sequence and regulates ap65-1 gene, which encodes a hydrogenosomal malic enzyme that may play a role in the cytoadherence of the parasite. Here, we identified tvMyb3_53–180 as the essential fragment for DNA recognition and report the crystal structure of tvMyb3_53–180 bound to MRE-1 DNA.

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Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus
Protein Science Apr 09, 2022
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Chemical Communications May 24, 2018
Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis
Scientific Reports Apr 03, 2018
In-depth study of DNA binding of Cys2His2 finger domains in testis zinc-finger protein
PLoS One Apr 06, 2017
Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
Nature Comm. Nov 12, 2015
Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae.
Nucl. Acids Res. Dec 25, 2013
Structural Basis of a Physical Blockage Mechanism for the Interaction of Response Regulator PmrA with Connector Protein PmrD from Klebsiella Pneumoniae.
J Biol Chem. Jul 16, 2013
Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation
Nucl. Acids Res. Sep 08, 2011
NMR structural analysis of DNA recognition by a novel Myb1 DNA-binding domain in the protozoan parasite Trichomonas vaginalis
Nucleic Acids Research. Feb 26, 2009
Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation.
J. Biol. Chem Sep 07, 2006

Dr. Chen, Chinpan 陳金榜博士

HIGHLIGHT DETAIL
重要成果詳細內容

Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation

List of Highlights
文件紀錄

Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus

Protein–DNA complex-guided discovery of the antibacterial lead E1 for restoring the susceptibility of Klebsiella Pneumoniae to polymyxin B by targeting the response regulator PmrA

Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis

In-depth study of DNA binding of Cys2His2 finger domains in testis zinc-finger protein

Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.

Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae.

Structural Basis of a Physical Blockage Mechanism for the Interaction of Response Regulator PmrA with Connector Protein PmrD from Klebsiella Pneumoniae.

Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation

NMR structural analysis of DNA recognition by a novel Myb1 DNA-binding domain in the protozoan parasite Trichomonas vaginalis

Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation.

HIGHLIGHT DETAIL重要成果詳細內容

Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation

List of Highlights文件紀錄

HIGHLIGHT DETAIL
重要成果詳細內容

List of Highlights
文件紀錄