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Dr. Chern, Yijuang

Distinguished Research Fellow
  • +886227899028 (Lab) (Room No: N333)
  • +886226523913 (Office)
  • 02-27829143 (Fax)

Specialty:
  • Signal Transduction
  • Gene Regulation
  • Neurodegeneration Disease

Education and Positions:
  • Ph.D. Univ. of Massachusetts


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The A2A adenosine receptor is a dual-coding gene: a novel mechanism of gene usage and signal transduction.

Dr. Chern, Yijuang
JBC, Nov 29, 2013

The A2A adenosine receptor (A2AR) is a G protein-coupled receptor and a major target of caffeine. The A2AR gene encodes alternative transcripts that are initiated from at least two independent promoters. The different transcripts of the A2AR gene contain the same coding region and 3′-untranslated region and different 5′-untranslated regions that are highly conserved among species.