Dr. Lee, Eminy H.Y.
Distinguished Research Fellow
- 02-27899125 (Lab) (Room No: 308)
- 02-27829224 (Fax)
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Specialty:
- Pathogenesis of and Neuroprotection against Alzheimer's Disease
- Molecular Mechanism of Mammalian Long-Term Memory Formation
Education and Positions:
Ph.D. Univ. of California, San Diego
Highlight Detail
NMDA receptor signaling mediates the expression of protein inhibitor of activated STAT1 (PIAS1) in rat hippocampus.
Dr. Lee, Eminy H.Y.
Neuropharmacology, Feb 01, 2013Protein inhibitor of activated STAT1 (PIAS1) was shown to play an important role in inflammation and innate immune response, but how PIAS1 is regulated is not known. We have recently demonstrated that PIAS1 enhances spatial learning and memory performance in rats. In this study, we examined the signaling pathway and neural mechanism that regulate PIAS1 expression in the brain by using pharmacological and molecular approaches.