HIGHLIGHT
重要成果
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- Stage Shift Improves Lung Cancer Survival: Real-World Evidence
- Journal of Thoracic Oncology, Sep 18, 2022
- Introduction Lung cancer is the global leading cause of cancer death. Taiwan initiated several health polic ......
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- Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications
- Small Methods, Feb 24, 2022
- Manipulation and precise delivery of optical energies in the regions of interest within specimens require diff ......
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- A siRNA targets and inhibits a broad range of SARS-CoV-2 infections including Delta variant
- EMBO Molecular Medicine, Feb 21, 2022
- The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants has altered the traject ......
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- Vorinostat combined with brigatinib overcomes acquired resistance in EGFR-C797S-mutated lung cancer
- Cancer Letters, Mar 26, 2021
- The development of a new generation of tyrosine kinase inhibitors (TKIs) has improved the treatment response i ......
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- PINK1-mediated inhibition of EGFR dimerization and activation impedes EGFR-driven lung tumorigenesis
- Cancer Research, Feb 09, 2021
- EGFR is established as a driver of lung cancer, yet the regulatory machinery underlying its oncogenic activity is not fully unders ......
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- Humanized COVID‐19 decoy antibody effectively blocks viral entry and prevents SARS‐CoV‐2 infection
- EMBO Molecular Medicine, Nov 30, 2020
- Abstract To circumvent the devastating pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, a hum ......
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- Antimetabolite pemetrexed primes a favorable tumor microenvironment for immune checkpoint blockade therapy
- Journal for ImmunoTherapy of Cancer, Nov 26, 2020
- Abstract Background: The immune checkpoint blockade (ICB) targeting programmed cell death-1 (PD-1) and its ligand (PD-L1) ha ......
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- Proteogenomics of Non-smoking Lung Cancer in East Asia Delineates Molecular Signatures of Pathogenesis and Progression
- Cell, Jul 09, 2020
- Summary Lung cancer in East Asia is characterized by a high percentage of never-smokers, early onset and predominant EGFR mutations. To ......
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- Nanomodified strategies to overcome EGFR-tyrosine kinase inhibitors resistance in non-small cell lung cancer
- Journal of Controlled Release, Jun 01, 2020
- Lung cancer is the primary cause of cancer-related death worldwide. 85%–90% of cases are non-small cell lung cancer (NSCLC) which char ......
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- Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein
- Journal of Medicinal Chemistry, Mar 26, 2020
- Drug resistance has been a major threat in cancer therapies that necessitates the development of new strategies to overcome this problem. We ......
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