c3.3-IgG is a chimeric antibody composed of the 3.3 anti-PEG variable region genes fused to human IgG1 constant domains. This antibody binds to the backbone of PEG and can be detected with anti-human secondary antibodies.
c3.3-IgG can be used as a IgG reference standard for anti-drug antibody assays (anti-PEG antibodies).
cAGP4-IgM is a chimeric antibody composed of the AGP4 anti-PEG variable region genes fused to human IgM constant domains. This antibody binds to the backbone of PEG and can be detected with anti-human secondary antibodies.
This antibody can be used as a IgM reference standard for anti-drug antibody assays (anti-PEG antibodies).
Hu-6.3 is a humanized high-affinity IgG1 antibody with similar binding as 6.3.
This antibody can be used as a IgG reference standard for anti-drug antibody assays (anti-PEG antibodies).
Hu-6.3 IgE is a human IgE antibody based on the 6.3 high affinity anti-PEG antibody.
This antibody can be used as a IgE reference standard for anti-drug antibody assays (anti-PEG antibodies).
c3.3-IgG2, c3.3-IgG3 and c3.3-IgG4 are chimeric antibodies composed of the 3.3 anti-PEG variable region genes fused to human IgG2, IgG3 or IgG4 constant domains, respectively. These antibodies can be detected with anti-human secondary antibodies and can be used as IgG subclass reference standards for anti-drug antibody assays (anti-PEG antibodies).
c3.3-IgG subclass kit contains four chimeric human IgG antibodies. All four antibodies possess the same variable regions (mouse 3.3 anti-PEG antibody) but different human heavy chains (IgG1, IgG2, IgG3 and IgG4).
c3.3/AGP4 subclass kit contains four chimeric human IgG anti-PEG antibodies and one chimeric human IgM anti-PEG antibody. The four IgG antibodies possess the same variable regions (mouse 3.3 anti-PEG antibody) but different human heavy chains (IgG1, IgG2, IgG3 and IgG4). The IgM antibody is made from the mouse AGP4 variable regions fused to human IgM.