PEG (polyethylene glycol) is a water-soluble, nontoxic, biocompatible polymer that has been approved by the Food and Drug Administration (FDA) for human intravenous, oral and dermal applications. Attachment of PEG chains to proteins can reduce their immunogenicity, minimize proteolytic cleavage and increase their serum half-life. PEG has also been attached to small molecules and liposomes for more selective delivery. PEG-modification of superparamagnetic iron oxide and quantum dots can improve their biocompatibility and reduce non-specific uptake.
To allow sensitive measurement of PEGylated compounds, we developed the first monoclonal antibody (AGP3) with specificity for PEG. Since then, we have produced a range of specific anti-PEG IgG and IgM monoclonal antibodies for use in ELISA, FACs, IHC and flow cytometry.
We strive to provide the highest quality anti-PEG antibodies and humanized anti-PEG antibody standards
20 years experience with anti-PEG antibodies
Rapid response to questions and orders
Our experience can help you succeed
We continue to develop and publish in this field
Consistently the highest quality antibodies
Choice of anti-PEG antibodies and standards
You can send an email to PEG@gate.sinica.edu.tw
You can also get technical help from Dr. Steve Roffler at the Institute of Biomedical Sciences, Academia Sinica sroff@ibms.sinica.edu.tw