MRI method development
Synaptic transmission and plasticity Ion channels Dendritic integration In-vitro and in-vivo patch-clamp recording Computational modeling
Magnetic resonance imaging (MRI) is extensively used in clinical and basic biomedical research. However, MRI detection of pH changes still p ...
BCL-2, a key protein in inhibiting apoptosis, has a 65-residue-long highly flexible loop domain (FLD) located on the opposite side of its li ...
Summary Eukaryotic mRNAs are 5′ end capped with a 7-methylguanosine, which is important for processing and translation of mRNAs. ...
Abstract Objectives: Fibromyalgia is commonly considered a stress-related chronic pain disorder, and daily stressors are known tri ...
The amyloid precursor protein (APP) intracellular domain (AICD) is implicated in the pathogenesis of Alzheimer’s disease (AD), but pos ...
Abstract We present a near-term treatment strategy to tackle pandemic outbreaks of coronaviruses with n ...
Abstract Proteins form complex biological machineries whose functions in the cell are highly regulated at both the cellular and mol ...
Background Alveologenesis is the final stage of lung development to form air-exchanging units between alveoli and blood vessels. Genetic ...
In E. coli dihydrofolate reductase, unusual conformational motions of a functional M20 loop that interacts with substrate and coenzyme have ...
The methyl-CpG-binding protein 2 gene, MECP2, is an X chromosome-linked gene encoding the MeCP2 protein, and mutations of MECP2 cause Rett s ...