Dr. Roffler, Steve R.
Distinguished Research Fellow
Division Chief
- 02-2652-3079 (Lab) (Room No: N233)
- 02-2782-9142 (Fax)
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Specialty:
- Antibody Engineering
- Directed Molecular Evolution
- Prodrugs
Education and Positions:
Ph.D. University of California, Berkeley
Dr. Roffler, Steve R. 's
Research Highlights
Antibodies against Poly(ethylene glycol) Activate Innate Immune Cells and Induce Hypersensitivity Reactions to PEGylated Nanomedicines
ACS Nano, Mar 16, 2023
Accelerated clearance by antibodies against methoxy PEG depends on pegylation architecture
Journal of Controlled Release, Jan 17, 2023
The interplay between membrane topology and mechanical forces in regulating T cell receptor activity
Communications Biology, Jan 11, 2022
Impact of anti-PEG antibody affinity on accelerated blood clearance of pegylated epoetin beta in mice
Biomedicine & Pharmacotherapy, Dec 06, 2021