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Dr. Roffler, Steve R.
Distinguished Research Fellow
Division Chief
02-2789-9152 (Lab) (Room No: N233)
02-2652-3079 (Office)
02-2782-9142 (Fax)
Specialty:
Antibody Engineering
Directed Molecular Evolution
Prodrugs
Anti-PEG antibodies
Nanomedicines
Education and Positions:
Ph.D. University of California, Berkeley
Dr. Roffler, Steve R. 's
Research Highlights
Dr. Roffler, Steve R. 's Lab
Dr. Roffler, Steve R. 's Research Highlights
Targeted internalization and activation of glycosidic switch liposomes by a biological macromolecule mPEG×EphA2 increases therapeutic efficacy against lung cancer
International Journal of Biological Macromolecules, Jan 20, 2025
Liposomes with Low Levels of Grafted Poly(ethylene glycol) Remain Susceptible to Destabilization by Anti-Poly(ethylene glycol) Antibodies
ACS Nano, Aug 09, 2024
Engineering stable and non-immunogenic immunoenzymes for cancer therapy via in situ generated prodrugs
Journal of Controlled Release, Feb 28, 2024
Interactions between nanoparticle corona proteins and the immune system
Current Opinion in Biotechnology, Oct 16, 2023
Antibodies against Poly(ethylene glycol) Activate Innate Immune Cells and Induce Hypersensitivity Reactions to PEGylated Nanomedicines
ACS Nano, Mar 16, 2023
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