Dr. Huang, Yi-Shuian
黃怡萱 博士
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Dysregulated proteostasis network in neuronal diseases
Frontiers in Cell and Developmental Biology, Feb 24, 2023
Long-term maintenance of synaptic connections is important for brain function, which depends on varying proteo ......
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Generation and Role of Calpain-Cleaved 17-kDa Tau Fragment in Acute Ischemic Stroke
Molecular Neurobiology, Aug 19, 2021
Stroke is the leading cause of permanent disability and death in the world. The therapy for acute stroke is still limite ......
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CPEB3-downregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice
Neuropsychopharmacology, May 03, 2021
Susceptibility or resilience to posttraumatic stress disorder (PTSD) depends on one's ability to appropriately adjus ......
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CMTR1-Catalyzed 2'-O-Ribose Methylation Controls Neuronal Development by Regulating Camk2α Expression Independent of RIG-I Signaling
Cell Reports, Oct 20, 2020
Summary Eukaryotic mRNAs are 5′ end capped with a 7-methylguanosine, which is important for processing and translation of mRNAs. ......
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CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis
Journal of Biomedical Science, Apr 15, 2020
Background Alveologenesis is the final stage of lung development to form air-exchanging units between alveoli and blood vessels. Genetic ......
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List of Highlights
文件紀錄
Dysregulated proteostasis network in neuronal diseases
Frontiers in Cell and Developmental Biology Feb 24, 2023
Generation and Role of Calpain-Cleaved 17-kDa Tau Fragment in Acute Ischemic Stroke
Molecular Neurobiology Aug 19, 2021
CPEB3-downregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice
Neuropsychopharmacology May 03, 2021
CMTR1-Catalyzed 2'-O-Ribose Methylation Controls Neuronal Development by Regulating Camk2α Expression Independent of RIG-I Signaling
Cell Reports Oct 20, 2020
CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis
Journal of Biomedical Science Apr 15, 2020
CPEB2‐dependent translation of long 3′‐UTR Ucp1 mRNA promotes thermogenesis in brown adipose tissue
EMBO J Sep 03, 2018
Olfactory-Experience- and Developmental-Stage-Dependent Control of CPEB4 Regulates c-Fos mRNA Translation for Granule Cell Survival
Cell Reports Nov 21, 2017
CPEB2 Activates GRASP1 mRNA Translation and Promotes AMPA Receptor Surface Expression, Long-Term Potentiation, and Memory
Cell Reports Nov 14, 2017
Decoding hidden messages in neurons: insights from epitranscriptome-controlled and specialized ribosome-controlled translation
Current Opinion in Neurobiology Nov 07, 2017
Deficiency of CPEB2-Confined ChAT Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction
The Journal of neuroscience Nov 03, 2016
Loss of CPEB3 Upregulates MEGF10 to Impair Mosaic Development of ON Starburst Amacrine Cells
Frontiers in Molecular Neuroscience Oct 24, 2016
NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress.
Nucl. Acids Res. Oct 07, 2015
Deletion of CPEB3 Enhances Hippocampus-Dependent Memory via Increasing Expressions of PSD95 and NMDA Receptors.
J Neurosci. Oct 23, 2013
NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3.
Nucleic Acids Res. Jun 22, 2012
Calpain 2 activated through the NMDA receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons.
MCB Jun 18, 2012
CPEB2–eEF2 interaction impedes HIF-1α RNA translation
EMBO J Dec 09, 2011
A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons.
Nucleic Acids Res. Jun 17, 2010
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