Dr. Shih, Chiaho 施嘉和 博士

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重要成果


  • Control and Eradication Strategies of Hepatitis B Virus
    Trends in Microbiology Jun 07, 2016
    Hepatitis B virus (HBV) is a major human pathogen, and chronic hepatitis can lead to cirrhosis and malignant hepatocellular carcinoma. While ......
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  • The Dual Role of an ESCRT-0 Component HGS in HBV Transcription and Naked Capsid Secretion.
    PLoS Pathog. Oct 02, 2015
    The Endosomal Sorting Complex Required for Transport (ESCRT) is an important cellular machinery for the sorting and trafficking of ubiquitin ......
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  • Immunodeficient Mouse Models with Different Disease Profiles by in vivo Infection with the Same Clinical Isolate of Enterovirus 71.
    J Virol. Aug 20, 2014
    Like poliovirus, severe infection with enterovirus 71 (EV71) can cause neuropathology. Unlike poliovirus, EV71 is often associated with hand ......
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  • Nucleic Acid Chaperone Activity Associated with the ARD Domain of Human Hepatitis B Virus Core Protein.
    J Virol. Dec 18, 2013
    Hepatitis B virus (HBV) DNA replication occurs within the HBV icosahedral core particles. HBV core protein (HBc) contains an arginine-rich d ......
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  • Identification of a Novel Antimicrobial Peptide from Human Hepatitis B Virus Core Protein Arginine-Rich Domain (ARD).
    PLOS Pathogens. Jun 13, 2013
    The rise of multidrug-resistant (MDR) pathogens causes an increasing challenge to public health. Antimicrobial peptides are considered a pos ......
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