癌症研究組從事癌症相關之診斷、治療、及致癌的分子機制研究。目前研發重點為延續前期研究成果,並在癌症發生、轉移的分子機制以及研發癌症治療藥劑方向做更深入探討。主要重點如下:
Mass spectrometry
Proteomics
Lung cancer is the most common cause of cancer-related mortality with more than 1.4 million deaths per year worldwide. To search for signifi ...
The B-cell translocation gene 3 (BTG3) is a member of the antiproliferative BTG gene family and a downstream target of p53. BTG3 also binds ...
Centriole duplication involves the growth of a procentriole next to the parental centriole. Mutations in STIL and CPAP/CENPJ cause primary m ...
Common genetic alteration in cancer genomes is implicated for embracing an aberrant cancer gene participated in tumor progression. In this s ...
Metastasis is a predominant cause of death in patients with cancer. It is a complex multistep process that needs to be better understood if ...
Small ubiquitin-like modifier (SUMO) conjugation and interaction are increasingly associated with various cellular processes. However, littl ...
Alternative splicing contributes largely to cell differentiation and functional specification. We previously reported that the RNA-binding p ...
Signal peptide-CUB-EGF-like domain-containing protein 3 (SCUBE3) is a secreted glycoprotein that is overexpressed in lung cancer tumor tissu ...
Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main cause of the Stevens–Johnson syndrome (SJS) and its related ...
Viruses rely on the host translation machinery to complete their life cycles. Picornaviruses use an internal ribosome entry site to initiate ...