Neuroscience
Cardiovascular & Metabolic Diseases
Infectious Disease & Immunology
Cancer
Research Highlights
Dr. Shieh, Sheau-Yann
Cell Death & Disease, Jul 18, 2022
JAK2-CHK2 signaling safeguards the integrity of the mitotic spindle assembly checkpoint and ge ......
Checkpoint kinase 2 (CHK2) plays an important role in safeguarding the mitotic progression, specifically the spindle assembly, though the mechanism of regulation remains poorly understood. Here, we identified a ...... MORE
Dr. Lin, Jung-Hsin
Frontiers in Molecular Biosciences, Jul 08, 2022
A Curvilinear-Path Umbrella Sampling Approach to Characterizing the Interactions Between Rapam ......
Rapamycin is an immunosuppressant macrolide that exhibits anti-proliferative properties through inhibiting the mTOR kinase. In fact, the drug first associates with the FKBP12 enzyme before interacting with the ...... MORE
Dr. Tao, Mi-Hua
Journal of Biomedical Science, Jul 07, 2022
A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody a ......
Background: With the continuous emergence of new SARS-CoV-2 variants that feature increased transmission and immune escape, there is an urgent demand for a better vaccine design that will provide broader ...... MORE
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