Cardiovascular & Metabolic Diseases

  • Elucidation of the structure/function of genes related to the normal physiology and pathophysiology of cardiovasuclar system
  • Investigation of cellular signaling and molecular mechanisms underlying the vaso-& cardioprotection and disease pathogenesis
  • Investigation of the in vivo gene functions using animal models of cardiovascular and metabolic diseases
  • Development of therapeutic approaches for cardiovascular diseases
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Hsieh, Patrick Ching-Ho
Distinguished Research Fellow
Division Chief
Specialty
1. Cardiac repair and regeneration
2. Microbiota and metabolism
3. Human induced pluripotent stem cells
4. Targeted delivery of nanomedicin
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Wu, Jer-Yuarn
Research Fellow
Specialty
  • Human Genetics
  • Pharmacogenetics
  • Genome Medicine
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Yang, Ruey-Bing (Ray)
Research Fellow
Specialty

Signal transduction

Receptor biology

Vascular biology

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Shyue, Song-Kun
Associate Research Fellow
Specialty
  • Caveolin-1
  • Protein Degradation
  • PGs & Cardiovascular Diseases
  • Adenovirus vector gene therapy
     
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Chen, Hung-Hsin
Assistant Research Fellow
Specialty
  1. Human Genome
  2. Genetic Epidemiology
  3. RNA-sequencing
  4. Biobank analysis
  5. Longitudinal analysis
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Lai, Shih-Lei (Ben)
Assistant Research Fellow
Specialty
  • Cardiovascular development and regeneration
  • Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease
  • Developmental genetics in fish models for human diseases
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Chen, Chien-Hsiun
Research Scientist
Specialty
  • Genetic Statistics
  • Genetic Epidemiology
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Chen, Yen-Hui
Research Scientist
Specialty
  • Laboratory Animal Science
  • Mouse phenotyping
  • Cardiovascular disease
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Chang, Yi-Cheng
Joint Appointment Associate Research Fellow
Joint
Specialty
  • Diabetes and Obesity
  • Genetic epidemiology
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Cheng, Ching-Feng
Joint Appointment Associate Research Fellow
Joint
Specialty
  • Integrative Physiology
  • Molecular Cardiology
  • Metabolic syndrome
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Hu, Yu-Feng
Joint Appointment Associate Research Fellow
Joint
Specialty

1. Cardiac arrhythmias

2. Electrophysiology

3. Biological pacemakers

4. Artificial intelligence

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Yang, Kai-Chien
Joint Appointment Associate Research Fellow
Joint
Specialty
  • Organ fibrosis and stromal biology
  • Cardiac regeneration
  • Non-coding RNA biology
  • Ion channel regulation and electrophysiology
  • Cardiac oxidative stress and arrhythmias
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Chen, Chien-Chang
Research Fellow
Cross Div.
Specialty
  • Chronic Pain
  • Calcium Channel
  • Cardiovascular Disease
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Hu, Che-Ming (Jack)
Associate Research Fellow
Cross Div.
Specialty

Biomaterials and Nanotechnology for Drug and Vaccine Development

Cardiovascular & Metabolic Diseases
- Research Highlights -
...
Dr. Yan , Yu-Ting
Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV.
Hum Mol Genet Nov 30, 2010

Glycogen storage disease type IV (GSD-IV) is an autosomal recessive disease caused by a deficiency in glycogen-branching enzyme (GBE1) activ ...

...
Dr. Hsieh , Patrick Ching-Ho
The enhancement of endothelial cell therapy for angiogenesis in hindlimb ischemia using hyaluronan.
Biomaterials Oct 01, 2010

Growing evidence shows that injection of hyaluronan (HA) benefits ischemic injury in animals. On the other hand, cell therapy is an emerging ...

...
Dr. Hsieh , Patrick Ching-Ho
Intramyocardial Peptide Nanofiber Injection Improves Postinfarction Ventricular Remodeling and Efficacy of Bone Marrow Cell Therapy in Pigs.
Circulation Sep 14, 2010

Growing evidence suggests that intramyocardial biomaterial injection improves cardiac functions after myocardial infarction (MI) in rodents. ...

...
Dr. Chen , Chien-Chang
Cav3.2 T-Type Ca2+ Channel-Dependent Activation of ERK in Paraventricular Thalamus Modulates Acid-Induced Chronic Muscle Pain.
J Neurosci. Aug 04, 2010

Treatments for chronic musculoskeletal pain, such as lower back pain, fibromyalgia, and myofascial pain syndrome, remain inadequate because ...

...
Dr. Yang , Ruey-Bing (Ray)
ATF3-Mediated Epigenetic Regulation Protects against Acute Kidney Injury.
JASN Apr 01, 2010

A variety of stress stimuli, including ischemia-reperfusion (I/R) injury, induce the transcriptional repressor ATF3 in the kidney. The funct ...

Highlights of all Divisions

Years