Cardiovascular & Metabolic Diseases

  • Elucidation of the structure/function of genes related to the normal physiology and pathophysiology of cardiovasuclar system
  • Investigation of cellular signaling and molecular mechanisms underlying the vaso-& cardioprotection and disease pathogenesis
  • Investigation of the in vivo gene functions using animal models of cardiovascular and metabolic diseases
  • Development of therapeutic approaches for cardiovascular diseases
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Hsieh, Patrick Ching-Ho
Distinguished Research Fellow
Division Chief
Specialty
1. Cardiac repair and regeneration
2. Microbiota and metabolism
3. Human induced pluripotent stem cells
4. Targeted delivery of nanomedicin
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Wu, Jer-Yuarn
Research Fellow
Specialty
  • Human Genetics
  • Pharmacogenetics
  • Genome Medicine
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Yang, Ruey-Bing (Ray)
Research Fellow
Specialty

Signal transduction

Receptor biology

Vascular biology

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Shyue, Song-Kun
Associate Research Fellow
Specialty
  • Caveolin-1
  • Protein Degradation
  • PGs & Cardiovascular Diseases
  • Adenovirus vector gene therapy
     
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Chen, Hung-Hsin
Assistant Research Fellow
Specialty
  1. Human Genome
  2. Genetic Epidemiology
  3. RNA-sequencing
  4. Biobank analysis
  5. Longitudinal analysis
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Lai, Shih-Lei (Ben)
Assistant Research Fellow
Specialty
  • Cardiovascular development and regeneration
  • Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease
  • Developmental genetics in fish models for human diseases
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Chen, Chien-Hsiun
Research Scientist
Specialty
  • Genetic Statistics
  • Genetic Epidemiology
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Chen, Yen-Hui
Research Scientist
Specialty
  • Laboratory Animal Science
  • Mouse phenotyping
  • Cardiovascular disease
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Chang, Yi-Cheng
Joint Appointment Associate Research Fellow
Joint
Specialty
  • Diabetes and Obesity
  • Genetic epidemiology
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Cheng, Ching-Feng
Joint Appointment Associate Research Fellow
Joint
Specialty
  • Integrative Physiology
  • Molecular Cardiology
  • Metabolic syndrome
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Hu, Yu-Feng
Joint Appointment Associate Research Fellow
Joint
Specialty

1. Cardiac arrhythmias

2. Electrophysiology

3. Biological pacemakers

4. Artificial intelligence

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Yang, Kai-Chien
Joint Appointment Associate Research Fellow
Joint
Specialty
  • Organ fibrosis and stromal biology
  • Cardiac regeneration
  • Non-coding RNA biology
  • Ion channel regulation and electrophysiology
  • Cardiac oxidative stress and arrhythmias
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Chen, Chien-Chang
Research Fellow
Cross Div.
Specialty
  • Chronic Pain
  • Calcium Channel
  • Cardiovascular Disease
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Hu, Che-Ming (Jack)
Associate Research Fellow
Cross Div.
Specialty

Biomaterials and Nanotechnology for Drug and Vaccine Development

Cardiovascular & Metabolic Diseases
- Research Highlights -
...
Dr. Hwang , Ming-Jing
A Critical Assessment of Information-guided Protein-protein Docking Predictions.
Mol Cell Proteomics. Dec 13, 2012

The structures of protein complexes are increasingly predicted by protein-protein docking (PPD) using ambiguous interaction data to help gui ...

...
Dr. Hsieh , Patrick Ching-Ho
Xenografted human amniotic fluid-derived stem cell as a cell source in therapeutic angiogenesis.
Int J Cardiol. Oct 06, 2012

The AFSC-ECs demonstrated endothelial cell characteristics in vitro. Four weeks later, AFSC-ECs transplantation significantly increased limb ...

...
Dr. Chen , Chien-Chang
The Cav3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.
Cardiovasc Res. Aug 10, 2012

Restenosis is an undesirable consequence following percutaneous vascular interventions. However, the current strategy for preventing resteno ...

...
Dr. Hsieh , Patrick Ching-Ho
Instructive Nanofiber Scaffolds with VEGF Create a Microenvironment for Arteriogenesis and Cardiac Repair.
Sci Transl Med. Aug 08, 2012

Angiogenic therapy is a promising approach for tissue repair and regeneration. However, recent clinical trials with protein delivery or gene ...

...
Dr. Hsieh , Patrick Ching-Ho
Treatment of acute thromboembolism in mice using heparin-conjugated carbon nanocapsules.
ACS Nano. Jul 24, 2012

The unsurpassed properties in electrical conductivity, thermal conductivity, strength, and surface area-to-volume ratio allow for many poten ...

Highlights of all Divisions

Years