2009 成果

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張程 博士
A New Scenario for Negative Functional Magnetic Resonance Imaging Signals: Endogenous Neurotransmission.
The Journal of Neuroscience. Mar 11, 2009

Functional magnetic resonance imaging (fMRI) has revolutionized investigations of brain functions. Increases in fMRI signals are usually ...

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陳金榜 博士
NMR structural analysis of DNA recognition by a novel Myb1 DNA-binding domain in the protozoan parasite Trichomonas vaginalis
Nucleic Acids Research. Feb 26, 2009

The transcription regulator, tvMyb1, is the first Myb family protein identified in Trichomonas vaginalis. Using an electrophoretic mobili ...

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陳垣崇 博士
Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data.
NEJM. Feb 19, 2009

Genetic variability among patients plays an important role in determining the dose of warfarin that should be used when oral anticoagulat ...

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林天南 博士
Ligand-Activated Peroxisome Proliferator–Activated Receptor-γ Protects Against Ischemic Cerebral Infarction and Neuronal Apoptosis by 14-3-3ε Upregulation.
Circulation Feb 16, 2009

Thiazolidinediones have been reported to protect against ischemia-reperfusion injury. Their protective actions are considered to be perox ...

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潘文涵 博士
Serum uric acid level as an independent risk factor for all-cause, cardiovascular, and ischemic stroke mortality: a Chinese cohort study.
Arthritis Rheum. Feb 15, 2009

The association between hyperuricemia and cardiovascular events has been documented in high-risk groups, but is still undetermined in gen ...

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謝小燕 博士
The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1.
Oncogene Jan 19, 2009

Cell cycle progression is monitored constantly to ensure faithful passage of genetic codes and genome stability. We have demonstrated pre ...

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陳建璋 博士
The CaV3.2 T-Type Ca2+ Channel Is Required for Pressure Overload–Induced Cardiac Hypertrophy in Mice.
Circulation Research. Jan 02, 2009

Voltage-gated T-type Ca2+ channels (T-channels) are normally expressed during embryonic development in ventricular myocytes but are undet ...

Years