林宜玲 博士Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity.
PLoS Pathogens, Jun 28, 2012
Dengue is one of the most important arboviral diseases caused by infection of four serotypes of dengue virus (DEN). We found that activation ......
黃怡萱 博士NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3.
Nucleic Acids Res., Jun 22, 2012
Cytoplasmic polyadenylation element-binding protein (CPEB)3 is a nucleocytoplasm-shuttling RNA-binding protein and predominantly resides in ......
黃怡萱 博士Calpain 2 activated through the NMDA receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons.
MCB, Jun 18, 2012
Long-term memory requires the activity-dependent reorganization of synaptic proteome to modulate synaptic efficacy and consequently consolid ......
趙麗洋 博士TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation.
Oncogene., Jun 11, 2012
The TRC8 gene, which was previously shown to be disrupted by a 3;8 chromosomal translocation in hereditary kidney cancer, encodes for an end ......
林小喬 博士DR_bind: a web server for predicting DNA-binding residues from the protein structure based on electrostatics, evolution and geometry.
Nucl. Acids Res, May 31, 2012
DR_bind is a web server that automatically predicts DNA-binding residues, given the respective protein structure based on (i) electrostatics ......
陳儀莊 博士Energy dysfunction in Huntington's disease: insights from PGC-1α, AMPK, and CKB.
Cell Mol Life Sci., May 25, 2012
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by a CAG trinucleotide expansion in the Huntingtin ( ......
陳垣崇 博士Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.
Nat Genet., May 25, 2012
To find new candidate loci predisposing individuals to Kawasaki disease, an acute vasculitis that affects children, we conducted a genome-wi ......
姚文萱 博士VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era.
Nucleic Acids Res., May 22, 2012
VarioWatch has been vastly improved since its former publication GenoWatch in the 2008 Web Server Issue. It is now at least 10 000-ti ......
林天南 博士Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) and Neurodegenerative Disorders.
Mol Neurobiol., May 21, 2012
As the growth of the aging population continues to accelerate globally, increased prevalence of neurodegenerative diseases, including Alzhei ......
神奈木玲兒 博士Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial–mesenchymal transition
PNAS, May 15, 2012
Sialyl Lewis x (sLex) and sialyl Lewis a (sLea) glycans are expressed on highly metastatic colon cancer cells. They promote ex ......
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