謝清河 博士Subcellular Localization of Survivin Determines Its Function in Cardiomyocytes
Theranostics, Oct 13, 2017
Rationale: Reducing cardiomyocyte death and enhancing their proliferation after myocardial infarction is perhaps the single largest challeng ......
陳建璋 博士Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus
Nature Communications, Oct 10, 2017
Myocardial infarction is the leading cause of death worldwide. Restoration of blood flow rescues myocardium but also causes ischemia-reperfu ......
楊瑞彬 博士FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation
Breast Cancer Research, Oct 05, 2017
Background
Core fucosylation (addition of fucose in α-1,6-linkage to core N-acetylglucosamine of N-glycans) catalyzed by fuco ......
楊瑞彬 博士Guanylyl cyclase‐G is an alarm pheromone receptor in mice
EMBO Journal, Sep 28, 2017
Many animals respond to threats by releasing alarm pheromones (APs) that warn conspecifics. In mice, detection of the AP 2‐sec‐butyl‐4,5‐dih ......
謝清河 博士Fenugreek Compound (N55) Lowers Plasma Glucose through the Enhancement of Response of Physiological Glucagon-like peptide-1
Scientific Reports, Sep 25, 2017
Glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) analogues are approved for treating type 2 diabetes, but are known to activate GLP-1R sign ......
林天南 博士Clinacanthus nutans Mitigates Neuronal Apoptosis and Ischemic Brain Damage Through Augmenting the C/EBPβ-Driven PPAR-γ Transcription
Molecular Neurobiology, Sep 23, 2017
Clinacanthus nutans Lindau (C. nutans) is a traditional herbal medicine widely used in Asian countries for treating a number of remedies inc ......
鄔哲源 博士A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
Nature Communications, Sep 12, 2017
Conjugation of polyethylene glycol (PEG) to therapeutic molecules can improve bioavailability and therapeutic efficacy. However, some health ......
周玉山 博士Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis
Oncotarget, Sep 08, 2017
Cellular metabolism of cancer cell is generally recognized to provide energy for facilitating tumor growth, but little is known about the ab ......
潘文涵 博士Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial
The American Journal of Clinical Nutrition, Sep 06, 2017
Background: Stroke is one of the leading causes of mortality and neurologic deficits. Management measures to improve neurologic outcomes are ......
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