楊世斌 博士

Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy

Journal of Biological Chemistry, Apr 06, 2022

      Pancreatic β-cells express ATP-sensitive potassium (KATP) channels, consisting of octamer complexes conta ......

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謝清河 博士

Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons

Cell Reports, Apr 05, 2022

      In this study, we establish a population-based human induced pluripotent stem cell (hiPSC) drug screening plat ......

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唐堂 博士

A novel HIF1α-STIL-FOXM1 axis regulates tumor metastasis

Journal of Biomedical Science, Apr 01, 2022

    Background Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps includi ......

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牟昀 博士

Fragment-Directed Random Mutagenesis by the Reverse Kunkel Method

ACS Synthetic Biology, Mar 24, 2022

      Two fundamentally different approaches are routinely used for protein engineering: user-defined mutagenesis an ......

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楊瑞彬 博士

Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness

Breast Cancer Research, Mar 18, 2022

      Background We recently showed that fucosyltransferase 8 (FUT8)-mediated core fucosylation of transforming g ......

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陳建璋 博士

Neuronal basis for pain-like and anxiety-like behaviors in the central nucleus of the amygdala

Pain, Mar 18, 2022

      Chronic pain is often accompanied by anxiety and depression disorders. Amygdala nuclei play important roles in ......

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楊世斌 博士

Potential cross-species correlations in social hierarchy and memory between mice and young children

Communications Biology, Mar 14, 2022

      Social hierarchy is associated with various phenotypes. Although memory is known to be important for hierarchy ......

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施嘉和 博士

CRM1-spike-mediated nuclear export of hepatitis B virus encapsidated viral RNA

Cell Reports, Mar 08, 2022

      Hepatitis B virus (HBV) is a global pathogen. We report here that the cellular CRM1 machinery can mediate nucl ......

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胡哲銘 博士

Integrated Design of a Membrane-Lytic Peptide-Based Intravenous Nanotherapeutic Suppresses Triple-Negative Breast Cancer

Advanced Science, Mar 04, 2022

      Membrane-lytic peptides offer broad synthetic flexibilities and design potential to the arsenal of anticancer ......

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楊瑞彬 博士

Urinary Galectin-3 as a Novel Biomarker for the Prediction of Renal Fibrosis and Kidney Disease Progression

Biomedicines, Mar 02, 2022

      Plasma galectin-3 (Gal-3) is associated with organ fibrosis, but whether urinary Gal-3 is a potential biomarke ......

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