Dr. Chen, Chih-Cheng
A role for substance P and acid-sensing ion channel 1a in prolotherapy with dextrose-mediated analgesia in a mouse model of chronic muscle pain
PAIN, May 01, 2022
Prolotherapy is widely used in pain control and tissue repair in pain medicine. The classical mode is injection with hyp ......
Dr. Lin, Wen-chang
Dominant transcript expression profiles of human protein-coding genes interrogated with GTEx dataset
Scientific Reports, Apr 28, 2022
The discovery and quantification of mRNA transcripts using short-read next-generation sequencing (NGS) data is ......
Dr. Jou, Yuh-Shan
Prognostic comparative genes predict targets for sorafenib combination therapies in hepatocellular carcinoma
Comput Struct Biotechnol J, Apr 20, 2022
With the increasing incidence and mortality of human hepatocellular carcinoma (HCC) worldwide, revealing innov ......
Dr. Mou, Yun
Development of a TNF-α-mediated Trojan Horse for Bacteria-based Cancer Therapy
Molecular Therapy, Apr 19, 2022
TNF-α is up-regulated in a chronic inflammatory environment, including tumors, and has been recognized a ......
Dr. Chen, Chinpan
Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus
Protein Science, Apr 09, 2022
In Staphylococcus aureus, vancomycin-resistance-associated response regulator (VraR) is a part of the Vra ......
Dr. Yang, Shi-Bing
Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy
Journal of Biological Chemistry, Apr 06, 2022
Pancreatic β-cells express ATP-sensitive potassium (KATP) channels, consisting of octamer complexes conta ......
Dr. Hsieh, Patrick Ching-Ho
Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons
Cell Reports, Apr 05, 2022
In this study, we establish a population-based human induced pluripotent stem cell (hiPSC) drug screening plat ......
Dr. Tang, Tang K.
A novel HIF1α-STIL-FOXM1 axis regulates tumor metastasis
Journal of Biomedical Science, Apr 01, 2022
Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps includi ......
Dr. Mou, Yun
Fragment-Directed Random Mutagenesis by the Reverse Kunkel Method
ACS Synthetic Biology, Mar 24, 2022
Two fundamentally different approaches are routinely used for protein engineering: user-defined mutagenesis an ......
Dr. Yang, Ruey-Bing (Ray)
Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness
Breast Cancer Research, Mar 18, 2022
We recently showed that fucosyltransferase 8 (FUT8)-mediated core fucosylation of transforming g ......