Dr. Lin, Yi-Ling Japanese Encephalitis Virus Nonstructural Protein NS5 Interacts with Mitochondrial Trifunctional Protein and Impairs Fatty Acid β-Oxidation.
PLoS Pathog., May 27, 2015Infection with Japanese encephalitis virus (JEV) can induce the expression of pro-inflammatory cytokines and cause acute encephalitis in hum ......
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Dr. Shen, Chen-Yang FGFR2 regulates Mre11 expression and double-strand break repair via the MEK-ERK-POU1F1 pathway in breast tumorigenesis.
Hum Mol Genet., May 18, 2015The association between breast cancer risk and genetic variants of fibroblast growth factor receptor 2 (FGFR2) has been identified and repea ......
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Dr. Chern, Yijuang Aberrant astrocytes impair vascular reactivity in huntington's disease.
Ann Neurol., Apr 25, 2015Objective Huntington's disease (HD) is an inherited neurodegenerative disease caused by the mutant Huntingtin gene (mHTT), which harbors ......
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Dr. Roffler, Steve R. Selective Delivery of PEGylated Compounds to Tumor Cells by anti-PEG Hybrid Antibodies.
Mol Cancer Ther., Apr 07, 2015Polyethylene glycol (PEG) is attached to many peptides, proteins, liposomes and nanoparticles to reduce their immunogenicity and improve the ......
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Dr. Yang, Pan-Chyr CXCL10/IP-10 is a Biomarker and Mediator for Kawasaki Disease.
Nat Commun., Mar 05, 2015Anticancer therapies are often compromised by nonspecific effects and challenged by tumour environments' inherent physicochemical and bi ......
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Dr. Chen, Yuan-Tsong CXCL10/IP-10 is a Biomarker and Mediator for Kawasaki Disease.
Circ Res., Jan 20, 2015We enrolled 214 children with fever and clinical features suggestive of KD. Of those, only 100 were diagnosed with KD. Their plasma samples ......
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Dr. Yang, Ruey-Bing (Ray)Disruption of Scube2 impairs endochondral bone formation.
J. Bone Miner. Res., Jan 12, 2015SCUBE2 (signal peptide-CUB-EGF domain-containing protein 2) belongs to a secreted and membrane-tethered multi-domain SCUBE protein family co ......
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